Browsing Doctoral Theses / Doktorsavhandlingar Institutionen för neurovetenskap och fysiologi by Title
Now showing items 126-145 of 477
-
Diagnostic Methods in Traumatic Brain Injury
(2017-04-20)Background: Traumatic brain injury (TBI) is a major cause of death and disability worldwide. Early detection and quantification of TBI is important for acute management, for making early accurate prognoses of outcome, and ... -
Diagnostic, Prognostic, and Disease Activity Biomarkers in Multiple Sclerosis
(2023-03-15)Multiple sclerosis (MS) is the most common immune-mediated disease of the central nervous system. While benign cases exist, if left untreated, MS results in the compounding accumulation of disability. In the last two ... -
Dietary patterns among older adults - With focus on dementia and related biomarkers
(2022-10-18)Background and aim: Diet is a lifestyle factor that can influence healthy ageing and the risk of developing dementia. Studies investigating dietary patterns among older adults in relation to dementia, and dementia-related ... -
Differences in glutamatergic transmission onto interneurons and pyramidal cells in the rat hippocampus
(2010-09-03)In the human brain there are about 100 billion excitatory glutamatergic neurons and 10 billion inhibitory GABAergic neurons. During development, these neurons are synaptically wired together into neural networks, functionally ... -
Diffusion Tensor Imaging and Tractography in Epilepsy Surgery Candidates
(2008-04-25)In selected patients with medically refractory epilepsy, surgical treatment can render the patients seizure free or significantly reduce seizure frequency. Temporal lobe resection (TLR) for temporal lobe epilepsy (TLE) is ... -
Diffusion Tensor Imaging and Tractography of the Visual Pathways
(2016-08-31)The visual pathways are essential for human vision, stretching from the retinas of the eyes, via the anterior visual pathways and the optic radiations, to the primary visual cortex in the occipital lobe. Injury to these ... -
DIGIROP prediction models for severe retinopathy of prematurity
(2023-05-04)BACKGROUND: Retinopathy of prematurity (ROP), a preventable, potentially blinding eye disease, is primarily diagnosed in extremely preterm infants. Gestational age (GA) and birth weight (BW) are the most prominent risk ... -
Direct triaging to physiotherapist in primary care - development and evaluation of a triage model
(2019-04-05)Background: There is evidence that early contact with physiotherapists leads to advantages for patients with musculoskeletal disorders. Many patients, however, initially seek contact with general practitioners (GPs) within ... -
Discovering the capabilities of ageing persons who are born abroad: crossing norms, moving health promotion forward
(2015-01-30)To improve the possibilities for the whole population to take control over their health is an important goal for health promotion and public health. Yet, with improved possibilities for international migration and extended ... -
DNA methylation profiling of CNS tumors; implications for clinical diagnostics
(2022-10-05)Diffuse gliomas and meningiomas are the most common primary tumors of the central nervous system (CNS) in adults and these tumors cause significant morbidity and mortality worldwide. Deregulation of the epigenetic mechanisms, ... -
Dopamine and the regulation of movements - significance of nigral and striatal dopamine release in normal, hemiparkinsonian and dyskinetic rats
(2009-02-02)Introduction: The nigrostriatal dopamine (DA) containing neurones are a pivotal component in the basal ganglia, a network that regulates movement. Degeneration of these neurones causes the cardinal symptoms of Parkinson’s ... -
Dopaminergic lnterference for Treatment of Schizophrenia and Alcohol Use Disorder - an experimental study in rats
(2022-05-27)The neurotransmitter dopamine is involved in several different physiological functions as well as pathological conditions. Two conditions that have been suggested to be related to a low dopaminergic tone in the ventral ... -
Dopaminergic stabilizers for the treatment of schizophrenia. Rat studies focusing on negative symptoms and mechanisms of action
(2007-11-21)Schizophrenia is a severe mental disorder manifested by positive, negative and cognitive symptoms. Current antipsychotic drugs have poor effects on negative and cognitive symptoms, thus necessitating the development of new ... -
Early detection of ESSENCE in Japanese 0-4-year-olds. Studies of neurodevelopmental problems in the community and in clinics
(2018-02-14)BACKGROUND: Early identification of children with neurodevelopmental problems/ESSENCE (Early Symptomatic Syndromes Eliciting Neurodevelopmental Clinical Examinations) is a critical issue both in the community and in clinical ... -
Early identification of primary health care patients at risk of sick leave due to work-related stress
(2023-03-02)Aim: Work-related stress and sick leave are common among primary health care patients, and general practitioners (GPs) often handle cases involving stress and work capacity in their daily practices. This thesis aimed to ... -
Eating disorders, eating pathology and ESSENCE
(2016-11-03)BACKGROUND: Eating and mealtime problems are among the most common problems in individuals with autism spectrum disorder (ASD). Despite this, no systematic way of exploring these problems has been available for persons ... -
The effect of astrocytes and reactive gliosis on neurogenesis and astrogenesis in mice
(2008-11-10)Astrocytes are the most common cell type in mammalian central nervous system (CNS). Glial fibrillary acidic protein (GFAP) and vimentin constitute intermediate filaments (known also as nanofilaments), a part of the ... -
The effect of massage for women with breast cancer
(2008-06-30)ABSTRACT Breast cancer is the most common type of cancer in females. The effect of massage in the field of oncology has been investigated to some extent. The present thesis explored the effect of light pressure effleurage ... -
Effects and experiences of exercise during pregnancy
(2015-09-25)Background: Recommendations regarding intensity, duration and type of exercise during pregnancy vary worldwide. Most research on exercise during pregnancy investigates the effects of aerobic exercise while only a few trials ... -
Effects of dietary fatty acids on the immune system
(2015-11-11)Sepsis is a deadly disease with an increasing incidence worldwide. Today, antimicrobials are the only effective pharmacological treatment. At the same time, bacteria, the pathogens behind most cases of sepsis, are becoming ...