• Improved fracture prediction by identifying and integrating novel risk factors in fracture risk assessment. 

  Zoulakis, Michail (2025-11-12)

  Abstract Osteoporosis causes significant morbidity and healthcare costs through fragility fractures, with substantial gaps remaining in fracture risk assessment, particularly in older women. This thesis presents four ...

• HEALTHCARE UTILIZATION AND LONG-TERM CARE IN INDONESIA’S AGEING POPULATION 

  RAMADANI, ROYASIA VIKI (2025-11-11)

  Background: Noncommunicable diseases (NCDs) are the leading cause of death worldwide, with cardiovascular diseases (CVDs) being the largest contributor. Seventy-three percent of NCD deaths occur in low- and middle-income ...

• Engineered extracellular vesicles for targeting and treating inflammation 

  Bergqvist, Markus (2025-11-11)

  Extracellular vesicles (EVs) are nanosized particles released by human and mammalian cells. They are emerging as therapeutic platforms due to their ability to facilitate intercellular communication and their immunomodulatory ...

• Modifierbara faktorer associerade till post-EVAR ruptur. Can post-EVAR rupture be prevented 

  Andersson, Mattias (2025-11-05)

  Background: Endovascular aortic repair has better short-term survival than open surgical repair but this advantage is lost over time. The main cause is rupture after EVAR. Its incidence has not decreased despite efforts ...

• Factors relevant for the outcome and for the prediction of cardiac arrest 

  Thuccani, Meena (2025-10-27)

  Even when treated, 30-day survival after cardiac arrest is low for in-hospital cardiac arrest (IHCA) (15-35%) and out-of hospital cardiac arrest (OHCA) (8%). In this thesis we aimed to investigate factors that affect ...

• Investigating the Association Between Household Gender Dynamics, Intimate Partner Violence, Mothers' Mental Health, Child Abuse, and Child Stunting in Rwanda 

  Utumatwishima, Jean Nepo (2025-09-29)

  Background: Many low- and middle-income countries still encounter the persistent challenge of child stunting, despite the widespread implementation of public health interventions aimed at reducing it. Most studies and ...

• Health, well-being, and outcomes after aortic valve replacement 

  Lachonius, Maria (2025-09-26)

  Background: Aortic stenosis is the most common heart valve disease requiring intervention. Without aortic valve replacement, the mortality is approximately 50% within 2 years after onset of severe symptoms. Aim: To ...

• PFAS elimination and PFAS effects on COVID-19 vaccine response 

  Andersson, Axel (2025-09-25)

  Background and aims: Per- and polyfluoroalkyl substances (PFAS) are persistent compounds, some of which have long serum half-lives in humans. Yet, details about how PFAS are eliminated from the human body are limited. PFAS ...

• Through Children’s Ears 

  Sandström, Loisa (2025-09-19)

  Background. In Sweden, nearly all children aged 4 to 6 attend preschool, making it a major source of daily indoor sound exposure. Existing standards are derived from adult occupational contexts and may not reflect children’s ...

• Gut microbiota metabolism linked to metabolic health and cardiovascular diseases 

  Mitteregger, Matthias Georg (2025-09-03)

  Positioned at the interface of nutrition and host physiology, the gut microbiota produces bioactive metabolites that modulate host lipid and glucose metabolism as well as immune function. Many of these metabolites, although ...

• Sex-specific responses to ischemic conditioning in myocardial infarction and stunning: Experimental insights 

  Elmahdy Soliman, Ahmed (2025-08-28)

  This thesis investigates how ischemic conditioning strategies interact with biological sex and hormonal status to modulate myocardial responses to ischemia-reperfusion injury. It addresses both irreversible myocardial ...

• Memory B Cells in Autoimmune Diseases 

  Nilsson Grimstad, Kristoffer (2025-08-19)

  B cells are central components of the adaptive immune system. On their surface, they express a B-cell receptor (BCR), a membrane-bound form of an antibody. Upon activation, B cells differentiate into either antibody-secreting ...

• Obesity treatment - examining the influence of eating behavior 

  Björkman, Sofia (2025-08-19)

  Background: Obesity is a complex, multifactorial chronic disease linked to severe co-morbidity, reduced quality of life, and lower life expectancy. Despite numerous treatment options, sustained long-term weight loss remains ...

• Extracellular Vesicles - Roles in mRNA-Based Therapies 

  Tangruksa, Benyapa (2025-05-20)

  Efficient and targeted delivery of therapeutic mRNA remains a major challenge in RNA-based medicine. This thesis explores how lipid nanoparticles (LNPs) and extracellular vesicles (EVs) cooperate in the delivery and ...

• Endovascular shunting techniques in vascular surgery 

  Millinger, Johan (2025-05-13)

  Abstract Background: Acute tissue ischaemia can lead to significant tissue damage and, in severe cases, permanent loss of organ or limb function. Temporary arterial shunting is an established technique to mitigate ...

• Computational phenotyping of obstructive airway diseases and allergy 

  Lisik, Daniil (2025-05-13)

  Allergy and obstructive airway diseases, e.g., asthma, are common and may inflict substantial hardship. They are also interlinked and heterogeneous in their clinical presentations (phenotypes). Artificial intelligence (AI) ...

• The role of the gut microbiota and frailty on bone metabolism, and the risk of injurious falls and fractures 

  Gregori, Giulia (2025-05-13)

  Aging is intrinsically linked to musculoskeletal decline, culminating in increased risk of frailty, falls, fractures, and associated morbidity and mortality. This thesis investigates the association between gut microbiota ...

• Birth weight and childhood overweight - exploring parental influences and future risk of coronary heart disease 

  Bramsved, Rebecka (2025-04-29)

  Overweight and obesity now affect individuals of all ages in all parts of the world. Obesity leads to individual suffering as well as increased risk of future disease and premature death from several causes, among which ...

• Cardiovascular and renal effects of long-term particle exposure 

  Kilbo Edlund, Karl (2025-04-25)

  Background and aims Long-term particle exposure is a major risk factor for cardiovascular disease, claiming millions of lives annually. However, it remains uncertain if atherosclerosis mediates the cardiovascular effects ...

• Evaluations of diet strategies in improving risk factor control in adults with type 1 diabetes 

  Sterner Isaksson, Sofia (2025-04-16)

  Achieving optimal glucose control remains challenging for many individuals with type 1 diabetes (T1D), leading them to explore various dietary strategies. However, evidence from dietary trials in T1D remains limited. The ...

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