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Vitamin D during pregnancy in relation to childhood growth, overweight and obesity
(2023-05-15)
The aim of this thesis is to investigate the association between maternal vitamin D intake and status in pregnancy and the child´s growth and risk of overweight and obesity in childhood. Data from the Norwegian Mother, ...
Vaccine responses after chemotherapy or stem cell transplantation in patients with hematological malignancies
(2022-09-22)
The prevention of infections in patients with hematological malignancies is important given the inherent immune deficiency associated with these diseases and the immunosuppressive effects of treatment. This thesis investigated ...
Free Fatty Acid Receptor 2 - A G protein coupled receptor with unique signaling properties in neutrophils
(2022-08-15)
The overall aim of the PhD thesis was to determine the role of neutrophil pattern recognition receptors in the initiation and resolution of inflammatory processes. Neutrophil pattern recognition receptors such as the formyl ...
Mechanical circulatory support in advanced heart failure - patient selection, treatment strategies and outcomes
(2022-09-19)
Background: Heart transplantation (HTx) remains the major treatment option for selected
patients with end-stage heart failure. In hemodynamically unstable patients, or when there is a
considerable risk of deterioration ...
Human stem cell-based in vitro model of cardiac hypertrophy
(2022-11-18)
Cardiac hypertrophy is an important and independent risk factor for the development of cardiomyopathy that may lead to heart failure. To accelerate the development of new and improved treatment options, relevant disease ...
Hypertoniscreening - Tidig upptäckt av högt blodtryck via tandvården
(2022-04-25)
Background: Hypertension is the main risk factor for the world’s total disease burden. This is of significance for public health at national level, for healthcare professionals, resource consumption and costs as well as ...
Endogenous sex hormones and cardiometabolic risk factors – population-based studies within the Skaraborg Project
(2022-12-21)
Cardiovascular diseases are the major contributors to mortality in
Sweden and globally. Men have a higher incidence of cardiovascular
diseases compared to women, until women reach the menopause.
Levels of sex hormones ...
Defining the clinical usefulness of vertebral fracture assessment
(2022-05-10)
Objective: Vertebral fractures (VFs) are the most common osteoporotic fracture and among the strongest predictors for future fracture. VFs can be identified by vertebral fracture assessment (VFA) from lateral spine imaging ...
Understanding the genetic architecture of fatty liver disease
(2022-11-29)
Non-alcoholic fatty liver disease (NAFLD) is currently the most common chronic liver disease, ranging from simple steatosis to more severe conditions, namely non-alcoholic steatohepatitis (NASH), liver fibrosis, cirrhosis, ...
Allergic and non-allergic asthma: Translational research in immunology
(2022-05-18)
Asthma is a chronic heterogeneous respiratory disease affecting more than 300 million people globally. The different phenotypes, including allergic and nonallergic asthma, are driven by different underlying mechanisms ...