Den 5/1-2026 kommer GUPEA att vara otillgängligt för alla under hela dagen.
Search
Now showing items 31-40 of 671
Free Fatty Acid Receptor 2 - A G protein coupled receptor with unique signaling properties in neutrophils
(2022-08-15)
The overall aim of the PhD thesis was to determine the role of neutrophil pattern recognition receptors in the initiation and resolution of inflammatory processes. Neutrophil pattern recognition receptors such as the formyl ...
Expression profiling of human macrophages and atherosclerotic plaques to identify genes and mechanisms that modulate the development of atherosclerosis
(2008-11-10)
Macrophages play an important role in atherosclerosis, a disease that affects large and
medium size arteries and causes clinical manifestations such as myocardial infarction or
stroke. The aim of this thesis was to ...
Importance of cardiac reserve for evaluation and prediction of cardiac function and morbidity assessed by low-dose dobutamine stress echocardiography
(2007-05-22)
This thesis aimed to evaluate the cardiac reserves capacity to be used to predict treatment effects, sub clinical heart disease and to evaluate b1-adrenoceptor (AR) gene polymorphism (Ser49Gly).
Studies were performed ...
Insulin resistance and cardiovascular function - Observational, translational and interventional studies
(2016-05-26)
Background: Microvascular disease is now recognized as an important driver for cardiovascular
mortality and morbidity. Diabetic patients are known to suffer from this condition, leading to e.g.
coronary ischemia as well ...
Nutritional metabolomics: The search for dietary exposure variables
(2018-10-19)
To establish associations and causation between diet and health, objective and reliable methods are needed to measure dietary exposure. Metabolomics provide an unbiased tool for exploring the modulation of the human ...
Myocardial creatine metabolism in experimental infarction and heart failure
(2007-10-04)
The failing heart is characterized by changes in structure, function and metabolism. All these changes are usually defined as
pathologic remodelling. An important part of this negative remodelling process is disturbances ...
Blood Pressure Elevation - Impact on Cardiovascular Structure and Endogenous Fibrinolysis
(2008-05-16)
Blood pressure elevation is a major risk factor for cardiovascular events and the risk increases in a dose-dependant manner. It is of importance to identify subjects prone to develop hypertension and adverse cardiovascular ...
Population-based studies on acute leukemias - lessons from the Swedish Adult Acute Leukemia Registry
(2011-09-12)
Acute leukemia (AL) is a rare, potentially curable, aggressive neoplasm of hematopoietic origin. AL is a heterogeneous disease and is further subdivided according to clinical and biological features.
The aims were to ...
Molecular genetics of patatin-like phospholipase domain-containing 3 and chronic liver disease
(2014-04-30)
Chronic liver disease is a major health burden worldwide. Major determinants of this condition are viral infections, alcohol abuse and obesity. Genetic background modulates the effect of damaging agents on the liver. The ...
Diagnosis & dietary intervention in patients with diabetic gastroparesis
(2013-09-03)
Background: Gastroparesis is a diabetic complication, which is often under-recognised. Existing treatment options are limited and diagnostic methods not easily accessible. Aims of the thesis: To compare two alternative ...