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Glucocorticoids - outcome in patients with glucocorticoid deficiency and Cushing's syndrome
(2012-05-15)
Glucocorticoids (GCs) are steroid hormones that have a major impact on human metabolism and are essential for life. Chronic GC overexposure, called Cushing’s syndrome, is characterized by central obesity, muscle atrophy, ...
Bone density, bone geometry and bone development in young men - the importance of pubertal timing and fracture history
(2015-03-30)
Background and objective: Peak bone mass, the maximal bone mass attained in young adulthood, is an important factor of the lifetime risk of developing osteoporosis. The aim of this thesis was to study the development of ...
A prospective chohort study on bone formation and bone loss in ankylosing spondylitis
(2019-10-02)
Background and objectives: Patients with ankylosing spondylitis (AS) have an increased risk of bone loss with development of osteoporosis and vertebral fractures (VFs) but also spinal new bone formation with growth of bony ...
Mortality and morbidity in patients with Addison's disease
(2015-02-27)
Addison's disease (AD) or primary adrenal insufficiency is a rare disease with an estimated prevalence of 100-140 per million inhabitants and deadly unless treated with glucocorticoids (GCs). Very limited information is ...
Determinants of Peak Bone Mass in Men
(2013-01-25)
Objective: The aim of this thesis was to identify, investigate and evaluate hereditary and environmental factors associated with peak bone mass or bone development in men.
Method: All studies in the thesis were performed ...
The role of physical activity on bone density and bone geometry in men
(2010-04-14)
THE ROLE OF PHYSICAL ACTIVITY ON BONE DENSITY AND BONE GEOMETRY IN MEN Introduction: Several studies indicate that peak bone mass, reached during the third decade in life, is an important determinant of osteoporosis later ...
Clinical study on osteoporosis in ankylosing spondylitis
(2013-03-25)
ABSTRACT
Ankylosing spondylitis (AS) is a disease characterized by chronic inflammation and osteoproliferation in the spine, leading to bony fusion (ankylosis) of the sacroiliacal joints, the growth of bony spurs ...
Long-term effects of growth hormone replacement in hypopituitary adults on body composition, bone mass and cardiovascular risk factors
(2012-11-06)
Growth hormone (GH) deficient (GHD) adults have decreased bone mass and muscle strength, impaired body composition, disturbed serum lipid pattern and increased morbidity and mortality in cardiovascular and cerebrovascular ...