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Fibrinogen, platelet and factor XIII supplementation in cardiac surgery: In vitro and in vivo studies
(2017-11-02)
Background: There is a high risk of bleeding complications in cardiac surgery. Fibrinogen and platelet concentrates are often used to treat perioperative bleeding, but there is little information about its efficacy. The ...
The IL-23 axis and innate immunity in the airways
(2017-11-08)
The Interleukin-23 (IL-23) axis is a communication system that integrates innate and adaptive
immunity. When triggered by microbial stimuli, antigen presenting cells can secrete the cytokine IL-23, leading to the production ...
Functional Modulation of the Pattern Recognition Formyl Peptide Receptors in Neutrophils - Lipopeptides - allosteric modulators of G-protein coupled receptors
(2017-01-20)
G-protein-coupled receptors (GPCRs), which are the largest class of cell-surface receptors, are involved in a range of physiologic processes and pathologies, making this a highly interesting group of proteins as targets ...
Cardiovascular risk factors in renal artery stenosis
(2017-05-11)
Renovascular hypertension (RVH) caused by atherosclerotic renal artery stenosis (ARAS) is
one of the most common forms of secondary hypertension. The prognosis for patients with
RVH is much worse compared to patients ...
Skilled birth attendant services in Nepal: overcoming barriers to utilization
(2017-05-18)
Background
Skilled birth attendants (SBAs) provide important services that improve maternal and newborn health and reduce maternal and newborn mortality. Utilization and coverage of SBA services reveal wide disparities ...
Early childhood thymectomy - impact on immune function
(2017-05-10)
Introduction: The thymus is the site of T cell maturation. Children born with a congenital heart defect often endure surgery early in life, and during surgery their thymus is routinely removed, as it blocks the surgeons ...
Prevalence and treatment of patients with heart failure with special emphasis on diuretics
(2017-09-21)
Background: Heart failure (HF) is a major health problem worldwide with an estimated prevalence of about 1-2% in the Western world. The temporal trend for prevalence of HF has never been investigated in a nationwide ...
Cortical porosity - Its regulation and association with fracture
(2017-04-11)
Objective: Osteoporosis is a disease characterized by low bone mineral density and
deteriorated bone microstructure. This thesis aimed to determine whether cortical
porosity is associated with previous fracture and ...
The impact of railway vibration and noise on sleep
(2017-09-25)
Sleep is a vital component of good health, and sleep loss is associated with impaired cognition, decreased psychomotor performance, cardiovascular disease, adverse effects on endocrine and metabolic function, negative mood, ...
Longitudinal Vitamin D Status During Pregnancy in a Swedish Cohort: The GraviD Study
(2017-04-20)
The aim of this thesis was to study vitamin D status among pregnant women in Sweden and if it was associated with gestational complications. A total of 2125 women were recruited at registration for antenatal care. Data ...