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Risk factors for fractures - a link between metabolic bone disease and cardiovascular disease
(2011-09-30)
Introduction: Fractures and cardiovascular disease (CVD) are a burden to society, as they result in high morbidity and mortality in both men and women.
Aim: The aim was to study prospectively modifiable risk factors for ...
Diabetes and obesity in primary health care - a condition beyond physiological factors
(2011-11-18)
Aims: The objectives of this thesis are to illustrate how obese and normal-weight individuals with type 2 diabetes (T2DM) experience their health status and health care interactions and to highlight the diabetes team ...
Analysis of Endogenous Particles in Exhaled Air
(2011-03-25)
Exhaled air contains non-volatile particulate material from the respiratory tract. The precise location in which exhaled particles are formed is unknown, and details on their chemical content are scarce. The aim of this ...
Population-based studies on acute leukemias - lessons from the Swedish Adult Acute Leukemia Registry
(2011-09-12)
Acute leukemia (AL) is a rare, potentially curable, aggressive neoplasm of hematopoietic origin. AL is a heterogeneous disease and is further subdivided according to clinical and biological features.
The aims were to ...
Pharmacological interventions against myocardial ischemia and reperfusion injury
(2011-11-09)
Background: Ischaemic heart disease is the leading cause of death in the industrialised world. Although the concept of early restoration of coronary blood-flow constitutes an important factor to reduce the injury caused ...
Loved ones within Palliative Care-understanding, strategies and need for support
(2011-04-15)
It is well known that during the palliative process both patient and loved ones have to face, and prepare themselves, for the patient´s approaching death. Their daily life will be marked by the disease, and physical, social, ...
Properties of the glomerular endothelial cell surface layer in vitro and in vivo.
(2011-03-25)
A healthy kidney produces final urine that is practically devoid of proteins and other physiologically important solutes. Tremendous amounts of fluid are filtered every day through the glomerular filtration barrier which ...
Renal hemodynamics in renal artery stenosis and angiotensin II-dependent hypertension. Pathophysiological and diagnostic aspects.
(2011-05-26)
Patients with renovascular hypertension have a poor renal and cardiovascular prognosis. To
improve the care of these patients, we need to increase knowledge about the pathophysiological mechanisms involved. Thus, the aims ...
Aspects on long-term treatment with tyrosine kinase inhibitors in Chronic myeloid leukemia
(2011-11-18)
Chronic myeloid leukemia (CML) is caused by the tyrosine kinase activity of the oncoprotein BCR-ABL. The introduction of tyrosine kinase inhibitors (TKIs) targeting BCR-ABL has profoundly changed the prognosis of CML. ...
Eosinophils, their progenitors and T helper cells in allergic airway inflammation
(2011-11-25)
Introduction: Asthma is a heterogeneous chronic lung disease associated with pronounced inflammatory
changes in the airways. Eosinophilic inflammation is the trait that is best linked to symptoms and
treatment responses ...