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Microarray analysis of gene expression in human adipocytes and adipose tissue
(2008-02-21)
Obesity has reached epidemic proportions worldwide and is associated with several serious conditions such as insulin resistance, type 2 diabetes, hyperlipidemia and atherosclerosis. Adipose tissue exerts important endocrine ...
Molecular mechanisms in obesity-associated metabolic disease
(2007-07-12)
Obesity is associated with increased morbidity and mortality. Subjects with obesity are at risk of developing several serious conditions such as type 2 diabetes, hypertension, coronary heart disease and stroke. This thesis ...
Fatty acids induce potentially atherogenic changes in extracellular matrix proteoglycans
(2007-09-10)
Insulin resistance and type 2 diabetes (T2D) are associated with an increased prevalence of atherosclerotic cardiovascular disease (CVD). A key step in the initiation of atherogenesis is retention of low density lipoproteins ...
The Role of Gut Dysfunction and Nutritional Factors in Liver Cirrhosis
(2007-03-14)
Malnutrition is a common finding in patients with liver cirrhosis. Malnutrition has been
shown to be associated with increased morbidity and mortality. Its pathogenesis remains
unclear but both poor dietary intake and ...