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A role of CD44 in atherosclerosis? Studies in mice and humans
(2009-01-12)
Atherosclerosis is an inflammatory disease that can lead to clinical complications such as myocardial infarction and stroke. Expressed in both vascular and inflammatory cells, adhesion molecule CD44 can be cleaved from the ...
The effect of hypoxia on macrophage proteoglycans: potential role in atherosclerosis
(2009-11-13)
A critical step in the development of atherosclerotic lesions appears to be the retention of low density lipoproteins (LDL) in the arterial wall, mediated by negatively charged proteoglycans (PG). Retained LDL is susceptible ...
Telefonrådgivning - en verksamhet i tiden : studier ur ett patient- och sjuksköterskeperspektiv
(2009-11-10)
Background : Care encounters and nurses’ advising over the phone are increasingly common in the Western
world today. This new area in the profession needs more research due to its’ importance in daily life.
Article I: ...
Quality of life, school performance, treatment adherence and gender differences in asthma.
(2009-10-19)
The aims of this thesis were to estimate the effectiveness of a computerized asthma education
program designed to suit young people (I), to analyze whether quality of life changed over a
five year period and whether young ...
Physical exposure, musculoskeletal symptoms and attitudes related to ICT use
(2009-05-20)
High prevalence of musculoskeletal symptoms/disorders in neck and upper extremities are reported among computer users. Considering the widespread use of information and communication technology (ICT) and mobile phones ...
Porcine myocardial ischemia-reperfusion studies on cardioprotection, ventricular arrhythmia and electrophysiology
(2009-11-19)
Background: Coronary artery disease is the primary cause of death in adults in the industrialised world and ventricular fibrillation associated with myocardial ischemia is the main cause of sudden cardiac death. Restoration ...
Activation of professional phagocytes with emphasis on the formyl peptide receptor family
(2009-05-08)
Phagocytic cells such as neutrophil granulocytes and monocytes are an essential part of our innate immune system and play an important role in the battle against pathogens. G-protein coupled receptors (GPCRs) and more ...
The Importance of Isoprenylation and Nf1 Deficiency in K-RAS-induced Cancer
(2009-11-10)
The RAS and RHO family proteins contribute to tumorigenesis and metastasis and belong to a family of so called CAAX proteins. The membrane targeting and proper function of CAAX proteins are dependent on posttranslational ...
THE ANGIOGENIC RESPONSE IN HYPOXIC HEART. Experimental studies in mice.
(2009-01-14)
Coronary artery disease is the leading cause of death in the western world today. Although
induction of angiogenesis would appear to be an ideal therapeutic strategy, clinical trials of proangiogenic
factors have proved ...
Glycaemic control: evaluation of HbA1c as a risk factor and the effect of modern insulins in clinical practice
(2009-04-02)
One of the ultimate goals of diabetes care is to minimise diabetic complications. When evaluating insulins it is important to understand what extent of improvements in glycaemic control is clinically relevant in preventing ...