Osteoporosis is a common age-related disease that increases the risk of fractures. Androgens are crucial for bone health in males. Although a substantial part of the effects of androgens on the skeleton is mediated via ...

As the treatment of Systemic Lupus Erythematosus (SLE) has become more effective the focus has partly shifted from main concern of short term morbidity and survival to long term complications such as osteoporosis. The aims ...

Background: Excess vitamin A is associated with decreased cortical bone and increased risk of fractures in humans. The aim of the present thesis was to assess the importance of vitamin A on the skeleton and bone cells in ...

Estrogen is involved in the regulation and development of reproductive organs. In addition, estrogen regulates several other organs including the skeleton, immune system, and adipose tissue. Estrogen treatment protects ...

Aims: The overall aim of this thesis was to study the effects of medical problems associated with spinal cord lesions on functioning - with special interest in work participation and sexual functioning. A special aim was ...

Introduction: Osteoporosis has been recognised as an established and well-defined disease that affects more than 75 million people in the United States, Europe and Japan. Osteoporosis has been operationally defined by the ...

The aim of this thesis was to describe the quality of drug treatment (QDT) regarding fall-risk increasing (FRIDs) and fracture-preventing (FPDs) drugs in older hip fracture patients, to evaluate a method for improving such ...

Rheumatoid arthritis (RA), a disease characterized by persistent joint inflammation and joint destruction, is frequently associated with generalized osteoporosis. A female preponderance (3:1) is present in RA, and ...

Addison's disease (AD) or primary adrenal insufficiency is a rare disease with an estimated prevalence of 100-140 per million inhabitants and deadly unless treated with glucocorticoids (GCs). Very limited information is ...

ABSTRACT In postmenopausal rheumatoid arthritis (RA), both the estrogen deficiency and the inflammatory disease contribute to the development of generalized osteoporosis. This leads to an increased risk of fracture, with ...