Browsing Doctoral Theses / Doktorsavhandlingar Institutionen för medicin by Subject "dendritic cells"
Now showing items 1-4 of 4
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Developmental and cholera toxin-induced alterations in the expression of intracellular signalling molecules
(2013-11-27)The innate immune system represents the first line of host defence that reacts promptly to attacks by microbes. This system relies on several families of pathogen-recognition receptors (PRRs), which recognize pathogen-associated ... -
Linking fms-like tyrosine kinase 3 and urokinase signalling to survivin expression in experimental arthritis
(2014-03-07)Rheumatoid arthritis (RA) is a systemic autoimmune joint disease, in which chronic inflammation and hyperplastic synovial tissue mediates destruction of cartilage and bone. Survivin is known as an intracellular inhibitor ... -
Molecular mechanisms behind the liver-induced acceptance of renal grafts in highly sensitized patients
(2009-12-18)Preformed antibodies directed at donor HLA are considered an absolute contraindication for kidney transplantation, because of the high risk of rejection. Thus, patients with high levels of HLA antibodies have little chance ... -
Tyrosine kinase Flt3/Flt3-ligand signaling in the modulation of immune responses in experimental arthritis
(2014-01-13)Rheumatoid arthritis (RA) is an autoimmune, chronic systemic inflammatory disorder that primarily affects flexible joints resulting in severe joint destruction and disability if left untreated. Today, advances in treatment ...