Browsing Doctoral Theses / Doktorsavhandlingar Institutionen för medicin by Subject "ICMT"
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Defining RCE1 and ICMT as Therapeutic Targets in K-RAS-induced Cancer
(2009-04-09)CAAX proteins, such as the RAS and RHO proteins, are recognized by a specific CAAX motif at the carboxyl terminus, which undergoes posttranslational modifications. First, a lipid group is attached to the cysteine (the “C”) ...