Browsing Doctoral Theses / Doktorsavhandlingar Institutionen för medicin by Subject "B cells"
Now showing items 1-5 of 5
-
B cell subpopulations in the pathogenesis of rheumatoid arthritis
(2019-04-04)B cell depleting therapy has proven to be an effective treatment in rheumatoid arthritis (RA), a disease characterized by the presence of autoantibodies against citrullinated proteins (ACPA) and the Fc portion of IgG ... -
Immune regulation by selective estrogen receptor modulators
(2015-04-30)At menopause, the levels of estrogen decline, leading to loss of estrogen-mediated protective effects on bone and an increased risk of osteoporosis. Hormone replacement therapy, containing estrogen, has been used for many ... -
Immunomodulation by estrogen and estren
(2007-03-02)Estrogen affects the development and regulation of the immune system. Treatment of gonadectomized mice with estrogen results in suppression of T and B lymphopoiesis, as well as decreased delayed type hypersensitivity ... -
The role of B cells in rheumatoid arthritis
(2012-03-26)It has been known for a long time that B cells play a role in rheumatoid arthritis (RA). By production of autoantibodies, presentation of auto-antigens and by producing cytokines B cells may contribute to the pathogenesis ... -
Thymic studies. Investigations into the effects of childhood thymectomy, and characterization of thymic B cells and Hassall's corpuscles
(2019-04-23)This thesis focuses on the human thymus, a primary lymphoid organ responsible for the maturation of T cells. Progenitors arrive from the bone marrow and start to randomly assemble their T cell receptor (TCR) followed by a ...