Browsing Doctoral Theses / Doktorsavhandlingar Institutionen för medicin by Title
Now showing items 338-357 of 555
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Nerve conduction and vibrotactile perception thresholds in female computer workers and hand-arm vibration-exposed male manual workers
(2010-10-22)Upper limb pain and disability are common problems, especially among working populations. The overall aim of this thesis was to investigate peripheral nerve function in the upper limb by nerve conduction test and vibration ... -
Neutrophil Function and Signaling Induced by Ligands for the Formyl Peptide Receptor 2
(2021-02-15)Neutrophil pattern recognition receptors belonging to the G-protein coupled receptor (GPCR) family play a role in the processes of initiation as well as resolution of inflammatory processes. Formyl peptide receptor 2 (FPR2) ... -
Neutrophil function in health and disease - role of intracellular radicals and galectin-3 as regulators of inflammation
(2013-11-14)The focus for this PhD project has been to investigate neutrophil functions in different (inflammatory) settings with specific focus on phagocyte-derived intracellular reactive oxygen species (ROS) as well as neutrophil ... -
Non-functioning pituitary adenomas and hypopituitarism - studies on morbidity and mortality
Background and aims: Hypopituitarism is most commonly caused by benign pituitary tumors, often resulting in insidious symptoms that develop over a long time. Due to either a mass effect exerted by the tumor, or due to the ... -
Non-functioning pituitary tumours - mortality, morbidity and tumour progression
(2014-04-16)Non-functioning pituitary tumours, i.e. non-functioning pituitary adenomas (NFPA) and craniopharyngiomas (CP), are histologically benign brain tumours. They are, however, associated with hypopituitarism, diabetes insipidus ... -
Non-invasive assessement of coronary flow velocity: Clinical and experimental studies
(2016-11-17)BACKGROUND AND OBJECTIVES Coronary flow velocity (CFV) and coronary flow velocity reserve (CFVR) evaluated by transthoracic ultrasound is a promising method to assess ischemic heart disease. CFVR is the ratio between ... -
Nonfatal injuries in a local context - Analysing social structures and perceptions in young people
(2012-05-24)Background: Injuries are a common health problem in children and young people. The uneven distribution over gender and socioeconomic groups is partly explained by factors at both the individual and family levels, but ... -
Nutritional impact on health in patients with Rheumatoid Arthritis
Objective: Rheumatoid Arthritis (RA) is the most common autoimmune rheumatic disease, affecting around 0.5-1% of the population. The aim of this thesis was to study dietary impact on markers of health in patients with ... -
Nutritional metabolomics: The search for dietary exposure variables
(2018-10-19)To establish associations and causation between diet and health, objective and reliable methods are needed to measure dietary exposure. Metabolomics provide an unbiased tool for exploring the modulation of the human ... -
Nya utmaningar, gamla strategier - om distriktsläkares yrkesroll och attityder till samarbete
(2008-11-10)Background: Being confronted by patients with incurable chronic and psychosocially complicated conditions constitutes one of the major challenges for today’s General Practitioners (GP). The traditional biomedical disease ... -
Obesity - surgical treatment and molecular mechanisms
(2015-11-11)Obesity is a condition of high prevalence and is associated with increased morbidity and mortality. Bariatric surgery is an effective treatment of obesity and reduces the risk for morbidity and mortality, but little is ... -
Obesity in diabetes. Cardiovascular outcomes and risk factor trajectories
(2021-03-23)Introduction: The association between body mass index (BMI) and mortality in diabetes is complex and sparsely investigated for cardiovascular (CVD) outcomes. We aimed to investigate these relationships among patients ... -
Obesity, Weight Loss and Cardiovascular Risk
(2020-05-26)Background: The global prevalence of obesity is on the rise, contributing to increased incidence and prevalence of cardiovascular morbidity and mortality. Obesity has adverse effects on cardiac structure and function, ... -
Obstructive Sleep Apnea in Cardiovascular Disease - Mechanisms and Impact of Treatment
(2015-10-29)ABSTRACT Background: Scientific understanding of obstructive sleep apnea (OSA) has increased exponentially during recent decades, suggesting a link between OSA and cardiovascular disease. Few randomized controlled trials ... -
Obstructive sleep apnea in coronary artery disease: Impact of CPAP treatment
(2016-04-05)Obstructive Sleep Apnea in Coronary Artery Disease: Impact of CPAP treatment Helena Glantz Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy at University of Gothenburg, ... -
Occupational heat exposure and kidney disease - Studies on the role of heat stress in the Mesoamerican epidemic of Chronic Kidney Disease of non-traditional origin
This thesis examines the association between heat stress and kidney disease in Mesoamerica using different perspectives and methods. An ecologic study found that hot, sugarcane-cultivating regions had elevated chronic ... -
On cellular sources for intimal hyperplasia after vascular interventions
(2007-05-24)Vascular interventions for the treatment of symptomatic atherosclerosis fail in up to 40 % of the cases during the first year. One important reason is the development of a narrowing process known as intimal hyperplasia ... -
On the causes of ventricular arrhythmia, its treatment and outcome
(2011-11-25)On the causes of ventricular arrhythmia, its treatment and outcome Christina Holmgren Institute of Medicine Sahlgrenska Academy at University of Gothenburg Göteborg, Sweden ABSTRACT Background: Ventricular arrhythmia ... -
On the effects of obesity treatment
(2021-05-12)Aim: In this thesis the effects of bariatric surgery in individuals with type 1 diabetes (T1D) will be assessed as well as the effects of surgery on risk for heart failure (HF) and atrial fibrillation (AF) in individuals ... -
On the regulation of immune responses to dietary and self antigens
(2010-02-04)Regulatory mechanisms are necessary to avoid the misdirected aggressive immune responses responsible for the pathology seen in autoimmunity and allergy. Thymic-derived CD4+CD25+ regulatory T cells are indispensible for ...