Browsing Doctoral Theses / Doktorsavhandlingar Institutionen för medicin by Title
Now showing items 248-267 of 606
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Health economic aspects of stroke: stroke prevention and effects on spouses' healthcare consumption and income
(2023-01-23)The overall aim of this thesis was to investigate two health economic aspects of stroke: (i) the clinical and cost-effectiveness of stroke prevention with left atrial appendage occlusion (LAAO) among persons with atrial ... -
Health hazards and cancer in relation to occupational exposures among Swedish seafarers
(2018-11-19)This thesis explores health hazards for seafarers in the Swedish merchant fleet, and occupational risks for lung cancer, mesothelioma and hematologic malignancy (HM). A special focus has been exposure to benzene and biomarker ... -
Health locus of control, depressive symptoms, and insulin resistance. Implications for treatment and prevention in general population and primary care
(2022-04-14)The disease burden of type 2 diabetes and depression is large and challenging for healthcare systems. Preventive interventions require resources and better knowledge concerning early stages in the development of these ... -
Health-Related Quality of Life and Growth Hormone Treatment
(2019-11-18)Introduction Growth Hormone (GH) is used to increase height in Turner Syndrome (TS), the most common sex-chromosome aberration in women. GH is also beneficial for bone mass. However, little is known about how GH treatment ... -
Hearing-related symptoms among women - Occurrence and risk in relation to occupational noise and stressful working conditions
(2018-05-24)A considerable amount of research has been devoted to the risk of noise-induced hearing loss among industry workers – the majority of whom are men. Much less research has been done in female-dominated human service ... -
Heart Failure and Aortic Stenosis - Factors Influencing Prognosis and Development
(2021-04-27)Background: An ageing population increases the prevalence of heart failure (HF) and aortic stenosis (AS). Several studies have investigated prognosis and predictors of HF with preserved ejection fraction (HFpEF) compared ... -
Heart failure and type 1 diabetes
(2018-03-27)Background: Approximately 45,000 individuals live with type 1 diabetes (T1D) in Sweden. Previous studies have shown an increased risk for heart failure in persons with diabetes, but most of the studies have been in the ... -
Heart failure epidemiology with emphasis on young adults
(2019-11-20)Background: Heart failure (HF) is a major health problem worldwide with exponentially increasing incidence with age and the majority of patients being elderly. In recent years, an increase in hospitalization and prevalence ... -
Heart failure in the elderly: clinical phenotype, prognosis and influencing factors
(2016-11-01)Background: Heart failure has high morbidity and mortality and the incidence increases with age. Most randomized studies in heart failure were conducted in younger heart failure patients, despite the fact that the majority ... -
Heart failure with reduced ejection fraction of ischaemic and non-ischaemic aetiology – Clinical characteristics, prognosis and factors associated with outcome
(2022-10-28)BACKGROUND: Ischaemic heart disease (IHD) is common in heart failure (HF) and is often considered to infer a worse prognosis. Following treatment improvements and the increased survival in both IHD and HF, patients are ... -
Hemodynamic, hemostatic and inflammatory effects of cardiotomy suction blood in cardiac surgery
(2013-10-14)ABSTRACT Background: Cardiac surgery with cardiopulmonary bypass induces an inflammatory response and a coagulopathy, which may contribute to perioperative complications. Retransfusion of unprocessed cardiotomy suction ... -
High Blood Pressure - Determinants and Risks
(2014-04-15)Aim: The overall aim of this thesis was to study determinants and risks associated with increasing blood pressure categories based on a combination of systolic and diastolic blood pressure ranging from optimal blood pressure ... -
Hip fracture prevention by screening and intervention of elderly women in Primary Health Care
(2007-09-18)Hip fracture prevention by screening and intervention of elderly women in Primary Health Care Daniel Albertsson Background – One in four Swedish women suffers a hip fracture (HF). In order to identify high-risk women we ... -
Host-Virus Interactions in Asthma and COPD
(2018-10-26)Asthma and chronic obstructive pulmonary disease (COPD) are associated with periods of worsened symptoms, known as exacerbations. Severe exac-erbations can result in hospitalisation, irreversible decline of the disease and ... -
How can we optimize bystander basic life support in cardiac arrest?
(2007-11-23)The aim of this thesis was to describe various aspects of cardiopulmonary resuscitation (CPR) and CPR training in order to find approaches for enhancing bystander interventions. Cardiac care patients (n=401) were interviewed ... -
Human response to wind turbine noise - perception, annoyance and moderating factors
(2007-05-23)Aims The aims of this thesis were to describe and gain an understanding of how people who live in the vicinity of wind turbines are affected by wind turbine noise, and how individual, situational and visual factors, as ... -
Human stem cell-based in vitro model of cardiac hypertrophy
(2022-11-18)Cardiac hypertrophy is an important and independent risk factor for the development of cardiomyopathy that may lead to heart failure. To accelerate the development of new and improved treatment options, relevant disease ... -
Humoral lmmune Response with Focus of lgG Glycosylation -In murine models
(2024-03-14)The humoral immune system orchestrates a vital defense mechanism through the secretion of antibodies, especially Immunoglobulin G (IgG), which actively targets and neutralizes foreign particles and pathogens. Glycosylation ... -
Hutchison-Gilford Progeria Syndrome – A new treatment strategy and the role of prelamin A in oncogenesis
(2014-04-25)Prelamin A, a CaaX-protein is a key structural protein of the inner nuclear lamina, a meshwork lining the inner nuclear envelope. Farnesylated prelamin A is cleaved just upstream of the farnesylcysteine residue to ... -
Hypertension and cardiovascular risk factors in women - a follow-up study forty years after hypertensive pregnancies
(2013-04-03)The aims of the thesis were to investigate the impact of pregnancy blood pressure, a current diagnosis of hypertension and blood pressure levels on neurohumoral, cardiovascular and metabolic status in postmenopausal women ...