Now showing items 1-4 of 4

    • Immunotherapy and immunosuppression in myeloid leukemia 

      Hallner, Alexander (2018-11-12)
      Acute myeloid leukemia (AML) and chronic myelomonocytic leukemia (CMML) are potentially life-threatening blood cancers characterized by the expansion of malignant myeloid cells in bone marrow and other organs. This thesis ...
    • Oxidant-induced cell death in lymphocytes: mechanisms of induction and resistance 

      Bergh Thorén, Fredrik (2007-04-16)
      Reactive oxygen species (oxidants, oxygen radicals) produced by the phagocytic NADPH oxidase have pivotal roles in immunity. Patients lacking a functional NADPH oxidase suffer from chronic granulomatous disease, which is ...
    • Redox reactions in cancer: impact and regulation 

      Grauers Wiktorin, Hanna (2018-09-28)
      The reduction-oxidation (redox) reaction involves a change in the oxidation state of molecules where a molecule that donates an electron is oxidized and a molecule that accepts an electron is reduced. The NADPH oxidase of ...
    • Targeting NOX2 in cancer 

      Aydin, Ebru (2018-02-27)
      Reactive oxygen species (ROS) are short-lived, toxic derivatives of oxygen that are produced during mitochondrial respiration and by NADPH oxidases (NOX). By enzymatically generating ROS, the myeloid cell NOX2 plays a ...