Browsing Doctoral Theses / Doktorsavhandlingar Institutionen för biomedicin by Subject "reactive oxygen species"
Now showing items 1-4 of 4
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Immunotherapy and immunosuppression in myeloid leukemia
(2018-11-12)Acute myeloid leukemia (AML) and chronic myelomonocytic leukemia (CMML) are potentially life-threatening blood cancers characterized by the expansion of malignant myeloid cells in bone marrow and other organs. This thesis ... -
Oxidant-induced cell death in lymphocytes: mechanisms of induction and resistance
(2007-04-16)Reactive oxygen species (oxidants, oxygen radicals) produced by the phagocytic NADPH oxidase have pivotal roles in immunity. Patients lacking a functional NADPH oxidase suffer from chronic granulomatous disease, which is ... -
Redox reactions in cancer: impact and regulation
(2018-09-28)The reduction-oxidation (redox) reaction involves a change in the oxidation state of molecules where a molecule that donates an electron is oxidized and a molecule that accepts an electron is reduced. The NADPH oxidase of ... -
Targeting NOX2 in cancer
(2018-02-27)Reactive oxygen species (ROS) are short-lived, toxic derivatives of oxygen that are produced during mitochondrial respiration and by NADPH oxidases (NOX). By enzymatically generating ROS, the myeloid cell NOX2 plays a ...