Browsing Doctoral Theses / Doktorsavhandlingar Institutionen för biomedicin by Subject "Natural killer cells"
Now showing items 1-5 of 5
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Function of natural killer cells in Helicobacter pylori infection and gastric cancer
(2011-02-22)Helicobacter pylori infection is one of the most wide-spread infections in the world and causes a chronic inflammation in the gastrointestinal mucosa characterised by increased production of IFN-γ and is associated with ... -
Immunotherapy and immunosuppression in myeloid leukemia
(2018-11-12)Acute myeloid leukemia (AML) and chronic myelomonocytic leukemia (CMML) are potentially life-threatening blood cancers characterized by the expansion of malignant myeloid cells in bone marrow and other organs. This thesis ... -
Impact of NK cell repertoires on immunotherapy in acute myelod leukemia
(2017-11-08)Natural killer (NK) cells are lymphocytes endowed with cytotoxicity against aberrant cells, including transformed and virus-infected cells. NK cell function is dictated by a fine-tuned interplay between activating and ... -
NK cell recognition of malignant cells - a CRISPR approach to define novel mediators
(2024-03-14)Natural killer (NK) cells are cytotoxic lymphocytes of the innate immune system, capable of eliminating malignant cells. Their activity is intricately regulated through a balanced interplay between activating and inhibitory ... -
On the role of Natural Killer cell immunogenetics for the outcome of immunotherapy in acute myeloid leukemia
(2022-02-14)Numerous studies have revealed that natural killer cells have fundamental roles as effector cells in myeloid leukemias. Thus, understanding NK cell-related biomarkers that influence clinical outcome are warranted. This ...