dc.contributor.author | Kvarnström, Niclas | |
dc.date.accessioned | 2017-05-18T09:09:15Z | |
dc.date.available | 2017-05-18T09:09:15Z | |
dc.date.issued | 2017-05-18 | |
dc.identifier.isbn | 978-91-629-0178-3 (pdf) | |
dc.identifier.isbn | 978-91-629-0177-6 (print) | |
dc.identifier.uri | http://hdl.handle.net/2077/51882 | |
dc.description.abstract | Live organ donors undergo extensive surgery to provide an organ that can be lifesaving
or improve the health and quality of life for the recipient. The thesis seeks important
knowledge that may be used to further reduce the donor risk for the live kidney
donor as well as for an entirely new group of living donors, the uterus donor. The
general aims were to investigate the outcome for the living kidney and uterus donor in
both organ specific measurements and quality of life in the recovery after donation, as
well as to investigate if there are markers indicating elevated risk for the donor.
Living kidney donors at the Department of Transplantation Surgery at the Sahlgrenska
Academy, Sahlgrenska University Hospital and the live uterus donors at the Department
of Obstetrics and Gynaecology at the Sahlgrenska Academy, Sahlgrenska University
Hospital, were recruited. The study types used herein included a crosssectional
study on long-term kidney function, analysis of internal quality register data
and prospective studies on both living kidney and uterus donors. Both objective and
quantified subjective data (Patient-Reported Outcome) were used for statistical analysis.
After an initial decrease, followed by the removal of one kidney at donation, the
kidney function increased over time after donation for years while later on it decreased
with donor age. The number of arteries did not seem to affect the initial increasing
capacity of the remaining kidney. The kidney donor was typically recovered both
physically and mentally after three months following donation and socioeconomic
factors may have influenced the recovery. The entirely new donor group, living uterus
donors, returned to their previous physical health and well-being after the donation.
In conclusion, implementation of the current guidelines on living donor evaluation and
care provides safe selection and minimize the donor risk although psychosocial and
socioeconomic factors may influence the recovery. | sv |
dc.language.iso | eng | sv |
dc.relation.haspart | I. Fehrman-Ekholm I., Kvarnström N., Söfteland J., Lennerling A., Rizell M., Odén A., Simonsson T.
Post-nephrectomy development of renal function in living kidney donors: a cross-sectional retrospective study.
Nephrology Dialysis Transplantation 2011; 26: 2377–2381. ::doi::10.1093/ndt/gfr161 | sv |
dc.relation.haspart | II. Kvarnström N., Fehrman-Ekholm I., Olausson M., Lennerling A. Is there an increased risk for hypertension or worse outcome in live kidney donors left with multiple (>1) renal arteries? | sv |
dc.relation.haspart | III. Kvarnström N., Fehrman-Ekholm I., Söfteland J., Olausson M., Lennerling A.
A prospective study on recovery after living kidney donation. | sv |
dc.relation.haspart | IV. Kvarnström N., Järvholm S., Johannesson L., Dahm-Kähler P., Olausson M., Brännström M.
Live Donors of the Initial Observational Study of Uterus Transplantation — Psychological and Medical Follow-Up Until 1 Year After Surgery in the 9 Cases.
Transplantation 2017; 101: 664 -670. ::doi::10.1097/TP.0000000000001567 | sv |
dc.subject | living donor | sv |
dc.subject | kidney | sv |
dc.subject | uterus | sv |
dc.subject | transplantation | sv |
dc.title | Living donor transplantation -outcome and risk | sv |
dc.type | text | eng |
dc.type.svep | Doctoral thesis | eng |
dc.gup.mail | niclas.kvarnstrom@gu.se | sv |
dc.type.degree | Doctor of Philosophy (Medicine) | sv |
dc.gup.origin | University of Gothenburg. Sahlgrenska Academy | sv |
dc.gup.department | Institute of Clincial Sciences. Department of Surgery | sv |
dc.gup.defenceplace | Torsdagen den 8 juni 2017, kl 13.00, Kammaren, Vita stråket 12, Sahlgrenska Universitetssjukhuset, Göteborg | sv |
dc.gup.defencedate | 2017-06-08 | |
dc.gup.dissdb-fakultet | SA | |