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Fluid biomarkers in Alzheimer¿s disease ¿ current concepts


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Title: Fluid biomarkers in Alzheimer¿s disease ¿ current concepts
Authors: Rosén, Christoffer
Hansson, Oskar
Blennow, Kaj
Zetterberg, Henrik
Issue Date: 21-Jun-2013
Publication type: article, peer reviewed scientific
Organization: Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg
Citation: Molecular Neurodegeneration. 2013 Jun 21;8(1):20
Abstract: Abstract The diagnostic guidelines of Alzheimer’s disease (AD) have recently been updated to include brain imaging and cerebrospinal fluid (CSF) biomarkers, with the aim of increasing the certainty of whether a patient has an ongoing AD neuropathologic process or not. The CSF biomarkers total tau (T-tau), hyperphosphorylated tau (P-tau) and the 42 amino acid isoform of amyloid β (Aβ42) reflect the core pathologic features of AD, which are neuronal loss, intracellular neurofibrillary tangles... more
ISBN: http://dx.doi.org/10.1186/1750-1326-8-20
Description: © 2013 Rosén et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
URI: http://hdl.handle.net/2077/33190
Appears in Collections:Articles / Institute of Neuroscience and Physiology

 

 

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