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Fluid biomarkers in Alzheimer¿s disease ¿ current concepts

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Title: Fluid biomarkers in Alzheimer¿s disease ¿ current concepts
Authors: Rosén, Christoffer
Hansson, Oskar
Blennow, Kaj
Zetterberg, Henrik
Issue Date: 21-Jun-2013
Publication type: article, peer reviewed scientific
Organization: Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg
Citation: Molecular Neurodegeneration. 2013 Jun 21;8(1):20
Abstract: Abstract The diagnostic guidelines of Alzheimer’s disease (AD) have recently been updated to include brain imaging and cerebrospinal fluid (CSF) biomarkers, with the aim of increasing the certainty of whether a patient has an ongoing AD neuropathologic process or not. The CSF biomarkers total tau (T-tau), hyperphosphorylated tau (P-tau) and the 42 amino acid isoform of amyloid β (Aβ42) reflect the core pathologic features of AD, which are neuronal loss, intracellular neurofibrillary tangles... more
Description: © 2013 Rosén et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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