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Nasopharyngeal carcinoma: past, present and future directions
(2007-12-07)
Nasopharyngeal carcinoma (NPC) is a rare disease in Sweden. The purpose of this thesis was to investigate the clinicopathological manifestations of the disease and its treatment outcomes in a cohort of Swedish NPC patients ...
Voice Rehabilitation and Functional Outcomes Following Radiotherapy for Laryngeal Cancer
(2014-11-12)
The overall aim of this thesis was to evaluate the effects of radiotherapy and voice rehabilitation on voice function and Health Related Quality of Life (HRQL) following treatment for laryngeal cancer.
Patients treated ...
Clinical and molecular studies of liposarcoma
(2007-05-21)
Aims: (1) To analyse clinicopathological characteristics, treatment and outcome of liposarcoma, and to determine whether, and how, the Scandinavian Sarcoma Group (SSG) treatment guidelines were followed; (2) to analyse ...
Experimental and population-based studies on colorectal cancer - Thymidine phosphorylase as a potential biomarker
(2014-09-05)
Background: Colorectal cancer (CRC) is one of the most common malignancies, and the only reliable treatment option for cure is surgery.
Method: Quantitative real-time polymerase chain reaction was used to analyze the ...
Towards a balanced radiotherapy workflow using practical solutions identified by field studies and simulations
(2021-10-26)
With increasing cancer incidence comes a higher demand for radiotherapy (RT). Resources available for RT, well-educated staff, and linear accelerators (linacs), are limited. To meet the increasing demand without violating ...
Remodelling of extracellular matrix in rectal cancer and preoperative radiotherapy
(2009-04-06)
BACKGROUND
Preoperative radiotherapy reduces local recurrence due to rectal cancer, but increases postoperative morbidity. The aim of this thesis was to study the impact of radiotherapy on extracellular matrix (ECM) ...
Brain tumors in children. Intervening with the aftermath: relapse and long term side effects
(2017-04-25)
After completing primary treatment, childhood brain tumor patients enter a follow-up phase. Follow-up is needed for two main reasons; to detect relapse and to diagnose late side effects. The overall aims of this thesis ...
Optimization of radiotherapy in locally advanced lung cancer
(2011-12-20)
Lung cancer is the leading cause of cancer death worldwide as well as in Sweden, where the incidence is around 3500 new cases per year. About 50% have distant metastases by the time of diagnosis and are treated with ...