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The use of fibrinogen in cardiac surgery patients-clinical and experimental studies
(2019-10-30)
BACKGROUND Cardiac surgery with cardiopulmonary bypass impairs hemostasis due to hemodilution and consumption of platelets and coagulation factors, such as fibrinogen. The aim of this thesis was to study the role of ...
Cardiopulmonary bypass and the kidney - studies on patients undergoing cardiac surgery
(2018-11-12)
Acute kidney injury is a common complication after cardiac surgery with cardiopulmonary bypass (CPB), and has a major impact on morbidity, mortality and costs. The mechanism of CPB-related renal impairment is not fully ...
Strain echocardiography in cardiac surgery - studies on the effects of loading conditions and inotropic agents on myocardial contraction and relaxation
(2019-12-19)
Background: Although reductions in myocardial contractility and relaxation are key compo-nents in heart failure (HF), assessment of them is difficult, as clinical measurements deal with a net effect of myocardial contractility, ...
Neurochemical and cognitive aftermaths of surgery - studies on short- and long-term effects of surgery and anesthesia
(2020-10-01)
Background: Each year, around the world, more than 230 million patients have surgery. Improvements in healthcare have resulted in older and sicker patients undergoing surgical interventions. As a result, surgical safety ...
Prevention and treatment of acute kidney injury after cardiac surgery
(2010-06-01)
Acute kidney injury (AKI) occurs frequently after cardiac surgery and is independently associated with increased mortality. The main cause of AKI in these patients is renal ischemia. However, data on the renal oxygenation, ...
Cardiac surgery and the kidney - studies on the effects of pharmacological interventions on renal perfusion, filtration and oxygenation
(2013-03-25)
Acute kidney injury (AKI) commonly complicates cardiac surgery and is associated with high mortality. Renal ischemia is considered to be the major cause. There is a close association between glomerular filtration rate ...
Acute kidney injury after cardiac surgery and heart transplantation - monitoring, prevention and treatment
(2022-10-14)
Background: Acute kidney injury (AKI) is a common and serious complication after cardiac surgery and heart transplantation, leading to increased morbidity and mortality. To date, there are neither proven clinical real-time ...
Levosimendan vs. Milrinone: Early Renal and Hemodynamic Outcomes after lnfant Cardiac Surgery
(2022-10-25)
Background: Myocardial and renal dysfunction are common after cardiac surgery in young children, which increases risk of complications and delayed recovery. Inodilators, such as milrinone and levosimendan, are frequently ...