BACKGROUND Cardiac surgery with cardiopulmonary bypass impairs hemostasis due to hemodilution and consumption of platelets and coagulation factors, such as fibrinogen. The aim of this thesis was to study the role of ...

Acute kidney injury is a common complication after cardiac surgery with cardiopulmonary bypass (CPB), and has a major impact on morbidity, mortality and costs. The mechanism of CPB-related renal impairment is not fully ...

Background: Although reductions in myocardial contractility and relaxation are key compo-nents in heart failure (HF), assessment of them is difficult, as clinical measurements deal with a net effect of myocardial contractility, ...

Background: Each year, around the world, more than 230 million patients have surgery. Improvements in healthcare have resulted in older and sicker patients undergoing surgical interventions. As a result, surgical safety ...

Acute kidney injury (AKI) occurs frequently after cardiac surgery and is independently associated with increased mortality. The main cause of AKI in these patients is renal ischemia. However, data on the renal oxygenation, ...

Acute kidney injury (AKI) commonly complicates cardiac surgery and is associated with high mortality. Renal ischemia is considered to be the major cause. There is a close association between glomerular filtration rate ...

Background: Acute kidney injury (AKI) is a common and serious complication after cardiac surgery and heart transplantation, leading to increased morbidity and mortality. To date, there are neither proven clinical real-time ...

Background: Myocardial and renal dysfunction are common after cardiac surgery in young children, which increases risk of complications and delayed recovery. Inodilators, such as milrinone and levosimendan, are frequently ...