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Intravoxel incoherent motion modeling - Optimization of acquisition, analysis and tumor tissue characterization
(2018-09-13)
Intravoxel incoherent motion (IVIM) analysis provides a means to obtain information on diffusion and perfusion from a single MRI sequence. The measurements are completely noninvasive and the results have been shown to be ...
Polycystic ovary syndrome - morphologic and dynamic evaluation by magnetic resonance imaging
(2013-05-10)
Polycystic ovary syndrome (PCOS) is a complex endocrine disorder, affecting up to 15% of women of reproductive age. The syndrome is characterized by oligo-anovulation, hyperandrogenism and polycystic ovaries. What constitutes ...
Invasive and Metastatic Properties of Advanced Prostate Cancer
(2009-05-15)
Prostate cancer is initially androgen-dependent (AD) and therefore androgen deprivation therapy (ADT) is generally used to treat advanced prostate cancer. However, the long-term treatment effects are insufficient and over ...
Optimized use of MRI in a PSA based prostate cancer screening program
(2021-05-07)
The overall aim of this thesis was to optimize different aspects of the use of MRI in screening for prostate cancer. Paper 1 was based on preoperative MRI in a prostatectomy cohort. Papers 2-4 were based on data from the ...
Ultrasonography for Diagnosis, Intervention and Follow-up in Juvenile Idiopathic Arthritis
(2011-11-25)
Early therapeutic intervention and the use of novel, highly effective treatments in juvenile idiopathic arthritis (JIA) have improved the outcome in many diseased children, but have also increased the need for more precise ...
Multiparametric MRI for evaluation of tumour treatment response
(2016-11-18)
Clinical assessment of tumour response to treatment largely relies on estimates of tumour size
by, e.g., measuring the largest tumour diameters on magnetic resonance (MR) or computed
tomography (CT) images, weeks or ...
Anterior cruciate ligament reconstruction using semitendinosus and gracilis autograft. Evaluation of the clinical outcome, radiographic findings, histology and biochemistry
(2015-05-18)
The present thesis focuses on different aspects of anterior cruciate ligament (ACL) reconstruction using hamstring tendon (HT) autografts. In Study I, two groups of patients were compared. One group underwent surgery in ...
Degenerative cervical myelopathy: Surgical treatment, imaging evaluation, and outcome
(2023-08-16)
Degenerative cervical myelopathy (DCM) is the most common cause of spinal cord
impairment in adults worldwide. The overall aims of this thesis were to compare
patient-reported clinical outcomes, adverse events, and ...
Advancements in DSC and BOLD perfusion imaging: Acquisition, analysis and clinical application
(2023-10-31)
This thesis is focused on perfusion MRI techniques and topics related to image acquisition, analysis and clinical applications. The first half of the thesis is focused on dynamic susceptibility contrast (DSC) MRI, a technique ...