Browsing Doctoral Theses / Doktorsavhandlingar Institutionen för kliniska vetenskaper by Subject "T cells"
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Checkpoint inhibitor-induced adverse events in the CNS - T-cell characteristics and biomarkers
(2023-08-21)Immune checkpoint inhibitors (ICI) activate T cells to kill cancer cells by blocking inhibitory receptors PD-1 (nivolumab; nivo) or CTLA-4 (ipilimumab; ipi). Activated T cells can also attack any healthy organ, causing ... -
Immunological effects of isolated regional perfusion in malignant melanoma
(2019-05-08)Malignant melanoma patients with metastatic disease confined to the limbs or liver may be treated with hyperthermic isolated regional perfusion with a chemotherapeutic agent, most commonly melphalan. This procedure enables ...