Browsing Doctoral Theses / Doktorsavhandlingar Institutionen för kliniska vetenskaper by Subject "Cancer"
Now showing items 1-6 of 6
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Advances in MRI based radiation therapy - Bringing MRl-only and multiparametric methods towards clinical applications
(2023-01-12)MRI data have the advantage of being excellent in soft tissue contrast, therefore having an increasing imaging role in external radiation therapy (RT). Lately, attention has been directed towards MRI-only workflows, with ... -
Barretts esophagus - aspects on early detection of malignant transformation
(2016-10-20)Background: Barrett’s esophagus (BE) is a metaplastic mucosal transformation adjacent to the gastroesophageal junction, due to chronic reflux of gastric juices. BE is associated to an increased risk of esophageal adenocarcinoma ... -
Multiparametric MRI for evaluation of tumour treatment response
(2016-11-18)Clinical assessment of tumour response to treatment largely relies on estimates of tumour size by, e.g., measuring the largest tumour diameters on magnetic resonance (MR) or computed tomography (CT) images, weeks or ... -
The proteasome as a target for cancer therapy
(2023-05-23)The main objective of this PhD thesis was to evaluate the significance of proteasome genes as prognostic markers for different cancer types and identify specific cancer forms that respond to proteasome inhibition. The ... -
TRISMUS Incidence, Effects on Health-Related Quality of Life and Development of the Gothenburg Trismus Questionnaire
(2013-11-18)The word trismus is modern latin, derived from the greek word ”trismos” meaning ”grinding” or ”rasping”. Trismus is defined as a limitation in the mouth/jaw-opening ability due to a reduced mandible mobility. A Maximal ... -
Using genetics to identify epigenetic and signal transduction targets in cancer
(2016-05-12)Cancer arises mostly due to the stepwise acquisition of untamed growth capabilities by various means, ranging from genetic, epigenetic to environmental factors. With the advancement made in molecular biology and associated ...