Browsing Doctoral Theses / Doktorsavhandlingar Institutionen för kliniska vetenskaper by Title
Now showing items 245-264 of 628
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Identification of novel growth hormone-regulated factors
(2009-11-27)The studies described in this thesis aimed to identify novel factors involved in the regulation of longitudinal growth and bone mineralization in response to growth hormone (GH) treatment. This was done by performing a ... -
Imaging of hip trauma - occult, suspect and concomitant fractures
(2016-04-05)Background: Between one and nine percent of all hip fractures are occult or suspect and further examinations with computed tomography (CT) and/or magnetic resonance imaging (MRI) are vital for further handling. Statistically ... -
Immunological effects of isolated regional perfusion in malignant melanoma
(2019-05-08)Malignant melanoma patients with metastatic disease confined to the limbs or liver may be treated with hyperthermic isolated regional perfusion with a chemotherapeutic agent, most commonly melphalan. This procedure enables ... -
Impact of the upper gut on body fluid regulation and blood pressure in man - potential involvement of a locally expressed renin-angiotensin system
(2011-05-26)This thesis explores the role of the upper gut in the regulation of diuresis and blood pressure control in relation to the novel finding of a mucosa-located renin-angiotensin system (RAS). RAS is a regulatory super-system ... -
Improved bioenergetic recovery during experimental ischemia and reperfusion by irradiation
(2007-11-16)Prolonged ischemia and reperfusion frequently occur during clinical operations. The bioenergetic status decreases during ischemia and reactive oxygen species (ROS) are formed during reperfusion, which may lead to irreversible ... -
Improvements in hip arthroplasty - did they work? Evaluations of different articulations and fixation concepts.
(2017-09-07)Today, total hip arthroplasty (THA) is one of the safest and most efficient surgical treatments. New materials, surgical techniques and design concepts intended to improve THA have not always been successful. Thorough ... -
Improving care of children with cancer in Egypt
(2013-12-23)Aims: More than 70 percent of the children diagnosed with cancer in Egypt die every year. In Sweden the corresponding figure is close to 20 percent. The aims of this study was to investigate psycho-oncological predictors ... -
Improving Emergency Medical System Response to Emergencies in a Middle-Income Country
(2017-03-16)Introduction: The main task for all Emergency Medical Services (EMS) is to save lives and be available to those with severe medical conditions. In both of the situations, a timely arrival by the ambulance is mandatory. ... -
In vitro wound healing characteristics of amelogenins
(2011-05-09)Wound healing involves the co-ordinated actions of several cell types, soluble cell mediators and extracellular matrix (ECM). This research project intended to investigate the role of certain ECM proteins in different ... -
Incidentally detected adrenal lesions - radiological aspects
(2011-10-10)Incidentally detected adrenal lesions (“adrenal incidentalomas”) have become a growing clinical problem due to increased and refined radiology methods. Autopsy studies show frequencies as high as 7-8% in the elderly. A ... -
Incidentally discovered adrenal tumours, adrenal metastases and pheochromocytomas - Clinical and epidemiological aspects.
(2011-04-15)With increasing use of high resolution radiological imaging incidentally discovered adrenal tumours (adrenal incidentalomas, AI) have become a common clinical problem. The aim of work-up and follow-up of patients with AI ... -
Infants with urinary tract infection - renal damage and risk factors
(2010-02-18)Background Identification of infants with urinary tract infection (UTI) who are at risk of renal scarring is an important clinical challenge with considerable economic consequences. Few issues in pediatric practice today ... -
INFLAMMATION AND PROSTATIC CARCINOGENESIS – A MORPHOLOGICAL STUDY OF THE HUMAN PROSTATE
(2008-03-07)ABSTRACT: Chronic inflammation has been suggested to be linked to cancers. Inflammatory infiltrates are often found in and around foci of prostatic atrophy. These foci, called proliferative inflammatory atrophy (PIA), are ... -
Inflammatory responses in minor and major surgical procedures
(2010-05-12)Surgical procedures promote an inflammatory response, correlating to the extent of the procedure performed and influencing outcome after surgery. The aims of the thesis were to investigate factors modulating the inflammatory ... -
Influence of inflammation and of stage of lung development on the development of neonatal lung injury
(2010-11-26)Bronchopulmonary dysplasia (BPD) is a major cause of mortality and long-term morbidity in prematurely born infants. Pulmonary inflammation, and abnormal alveolar and vascular development of the lung are histological ... -
Influence of postoperative treatment, surface treatment and stem design on the outcome of primary total hip arthroplasty
(2009-05-20)Aims: The aim of this study was to investigate the influence of postoperative treatment, surface treatment and stem design on the outcome of primary Total Hip Arthroplasty. The main intention was to study anteverted femoral ... -
Inguinal Hernia after Urologic Surgery in Males with Special Reference to Radical Retropubic Prostatectomy. A Clinical, Epidemiological and Methodological Study
(2006-10-02)Background and aims: In 1996 the first report indicating that inguinal hernia (IH) was a complication to radical retropubic prostatectomy (RRP) was published. The main aims of this thesis were to further establish this ... -
Initiation of Protein Biosynthesis in Skeletal Muscles at Feeding
(2010-05-28)Background and aim. Artificial nutrition by intravenous feeding has for decades indicated less than optimal support of whole-body protein metabolism and balance during some treatment conditions. Therefore, the present ... -
Insights from combining Action Research and System Dynamics when facilitating change and improvement processes in healthcare
(2022-09-30)BACKGROUND Healthcare is a complex system with multi-professional staff and multiple patient care pathways. Time pressure and minimal margins for error makes it challenging to implement new policies or procedures, no ... -
Integrative genomic and survival analysis of breast tumors
(2012-11-14)With the continued accumulation of genomic data at ever increasing resolution the challenge ahead lies in reading out meaningful clinical/biological information form the data that can contribute to a better understanding ...