Browsing Doctoral Theses / Doktorsavhandlingar Institutionen för kliniska vetenskaper by Title
Now showing items 523-542 of 632
-
Small-Scale Absorbed Dose Modelling in Selective Internal Radiation Therapy
(2015-04-30)Radioembolisation (RE), with yttrium-90 (90Y) labelled microspheres, is an increasingly common treatment method for unresectable liver tumours. The tolerable mean absorbed dose for normal liver (NL) tissue is higher in RE ... -
Small-scale dosimetry methods for normal tissues after radioembolization and peptide receptor radiotherapies; a focus on the liver parenchyma and the bone marrow
(2023-05-23)Radionuclide therapies are increasingly used in cancer treatments as they have been proven to be both effective and safe. As biodistributions and uptake vary widely between patients, a standardized approach is bound to ... -
Spinal column and hip joint changes, and their correlation to back pain in young athletes - Radiological and Clinical Studies
(2021-10-29)Background: Young athletes are at increasing risk for spinal column injuries and back pain due to excessive sporting activities, with potential development of complications ... -
Spino-pelvic sagittal alignment and back and hip pain prevalence in young elite athletes
(2017-02-23)Young athletes that perform regular intense training and sports competions have been shown to increase the risk of low back pain (LBP). This may be the result of heavy loading in different planes to the spine, heavy training ... -
ST analysis of the fetal ECG as an adjunct to fetal heart rate monitoring in labour-a clinical validation
(2009-05-06)The ability to make an accurate assessment of fetal well-being during labour is a great challenge. Animal and human studies have shown that fetal hypoxemia during labour can alter the shape of the fetal electrocardiogram ... -
Stent treatment of perforated duodenal ulcer - physiology and clinical aspects
(2021-03-30)Background The incidence of perforated duodenal ulcer is decreasing but still constitutes a life-threatening complication to peptic ulcer disease. Abdominal contamination from gastric or duodenal content occurs during ... -
Sterile water injections and acupuncture as treatment for labour pain
(2006-09-28)Most women experience pain during labour. Complementary pain relief methods such as sterile water injections and acupuncture are two alternatives for the child birthing women. The lack of knowledge about the use of these ... -
Strain echocardiography in cardiac surgery - studies on the effects of loading conditions and inotropic agents on myocardial contraction and relaxation
(2019-12-19)Background: Although reductions in myocardial contractility and relaxation are key compo-nents in heart failure (HF), assessment of them is difficult, as clinical measurements deal with a net effect of myocardial contractility, ... -
Strain echocardiography in the critically ill patient
(2019-04-12)In this thesis, strain echocardiography by two-dimensional speckle tracking imaging (2D-STI), was used for the evaluation of left ventricular (LV) and right ventricular (RV) function in critically ill patients with septic ... -
Strategies for optimisation of 177Lu-octreotate therapy – exploring local administration and combination therapy regimens
(2019-04-12)Neuroendocrine tumours (NETs) are a group of heterogeneous tumour types that originate in hormone-producing organs. Patients with NETs are often diagnosed after the primary tumour has metastasised. One treatment option for ... -
Stress-induced cardiomyopathy - clinical and experimental studies
(2015-10-23)Background: Stress-induced cardiomyopathy (SIC) is an acute cardiac condition with akinesia in the left ventricle (LV) that can be severe. A stress-trigger, physical or emotional, is usually identified preceding onset of ... -
Studies of cerebral blood flow and cerebrospinal fluid in childhood acute lymphoblastic leukemia
(2008-04-03)Acute lymphoblastic leukemia (ALL) is the most common childhood malignancy and more than 80% of the patients are cured today. Treatment might cause side effects and central nervous system (CNS) irradiation has been replaced ... -
Studies of molecular features and novel prognostic biomarkers of cutaneous melanoma
(2022-11-22)Cutaneous malignant melanoma is a highly heterogeneous disease. Immunotherapy has revolutionized the treatment of stage IV disease and is now successfully administered as adjuvant treatment in stage III and soon in stage ... -
Studies of Sunscreens: Percutaneous Absorption of Benzophenone-3 and Photostability
(2006-10-20)Studies of Sunscreens: Percutaneous Absorption of Benzophenone-3 and Photostability Helena Gonzalez Department of Dermatology and Venereology Institute of Clinical Sciences The Sahlgrenska Academy at Göteborg ... -
Studies of tibial fractures using the Swedish Fracture Register
(2019-09-13)This thesis has two topics. First, the creation and application of the Swedish Fracture Register (SFR) is described. Second, a series of studies of tibial fractures based on data from the SFR follows. Until the start ... -
Studies on colonization and infection with Staphylococcus aureus and other microbes in skin disease
(2012-11-22)The skin is colonized with a wide range of microbes. Some offer vital protection from colonization and infection with pathogenic strains while others have the capacity to cause or exacerbate disease. The aim of this thesis ... -
Studies on glycosphingolipids in regenerative medicine
(2014-05-09)Regenerative medicine, including stem cell based therapies and xenotransplantation, is a new and developing field that aims to restore normal function in end stage cell/organ failure. However, in therapeutic settings ... -
Studies on nutrition, body composition and bone mineralization in healthy 8-yr-olds in an urban Swedish community
(2009-09-30)Background: The incidence of welfare diseases including overweight in childhood is increasing worldwide. The results from a study of healthy pre-school children showed that in a population with well educated parents 17% ... -
Studies on pathophysiological mechanisms in experimental models of acute renal failure
(2007-02-19)Acute renal failure (ARF) affects 5-20 % of critically ill patients and is an independent risk factor for death in this patient population. Reactive oxygen species, thrombin and endothelin-1 (ET-1) are increased in ARF, ... -
Sudden infant death syndrome-epidemiology and environmental factors. Prevention is still a challenge
(2016-01-13)Sudden infant death syndrome (SIDS) is still an important cause of death in infancy despite its declining incidence. The overall aim of this thesis was to study environmental factors influencing the risk of SIDS with the ...