Browsing Doctoral Theses / Doktorsavhandlingar Institutionen för kliniska vetenskaper by Title
Now showing items 440-459 of 632
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Photdynamic therapy for treatment of Acne Vulgaris in clinical studies; dose response and mode of action
(2009-04-30)This thesis deals with the use of photodynamic therapy (PDT) for treatment of Acne Vulgaris. Acne Vulgaris is one of the most common skin disorders. Conventional treatments target the pathogenic factors and include a variety ... -
Photodynamic therapy- pain and aspects of pain relief
(2011-11-28)Photodynamic therapy – pain and aspects of pain relief Christina Halldin Department of Dermatology and Venereology, Sahlgrenska University Hospital, Institute ... -
Physical Exercise in Cystic Fibrosis -studies on muscle strength, oxygen uptake and lung function in young adult patients
(2008-08-12)Muscular strength, lung function and exercise capacity are internationally reported to be markedly impaired in adult patients with cystic fibrosis (CF). Since 20 years physical exercise is one important part in the treatment ... -
Polycystic ovary syndrome - morphologic and dynamic evaluation by magnetic resonance imaging
(2013-05-10)Polycystic ovary syndrome (PCOS) is a complex endocrine disorder, affecting up to 15% of women of reproductive age. The syndrome is characterized by oligo-anovulation, hyperandrogenism and polycystic ovaries. What constitutes ... -
Polycystic ovary syndrome in a lifetime perspective
(2020-12-08)Background: Polycystic ovary syndrome (PCOS) is common, affecting 9-18% of women. PCOS is associated with symptoms due to hyperandrogenism and ovarian dysfunction, but is also associated with the metabolic syndrome including ... -
Polycystic ovary syndrome: ovarian pathophysiology and consequences after the menopause
(2011-11-18)Polycystic ovary syndrome Ovarian pathophysiology and consequences after the menopause Johanna Schmidt Institute of Clinical Sciences at Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden, 2011 The ... -
Postoperative pain management in planned lumbar spine surgery: Implementing structural changes in a complex healthcare setting
(2021-01-18)BACKGROUND Poorly managed postoperative pain (POP) continues to cause suffering and prolong hospital care, affecting patients, individual health care professionals, and team strategies and attitudes. The impact on these ... -
Potential Therapeutic Applications of Novel Bioengineered Tissues and Organs Using Methods of Decellularization and Recellularization
(2018-09-04)The transplantation of personalized organs or tissues will benefit patients with various diseases and disorders. Decellularization is a method to generate an acellular, non-immunogenic natural scaffold. The personalized ... -
Predicting mortality by comorbidity for patients with hip arthroplasty: Prospective observational register studies of a nationwide Swedish cohort
(2020-08-19)INTRODUCTION: Patients with total hip arthroplasty (THA) due to osteoarthritis (OA) are usually healthy, some with a remaining lifetime of several decades after surgery. Patients with hip arthroplasty due to a femoral ... -
Prediction of embryo viability by morphology and metabolomic profiling
(2013-01-25)Abstract The ultimate challenge for all in vitro fertilisation (IVF) clinics is to develop the ability to select for transfer the best single embryo first, from the patient’s cohort of embryos, thereby maximising the ... -
Prediction value of genetic and neuromarkers in blood and liquor in patients with severe traumatic brain injury
(2015-03-30)Background: Severe traumatic brain injury (sTBI) is the most common cause of mortality in young adults. sTBI induces variable brain damage, invisible in Computer Tomographic scans early post-trauma. Further, neurology ... -
Predictors of Complications after Anterior Cruciate Ligament Injury
(2015-04-10)BACKGROUND: An anterior cruciate ligament (ACL) tear is a serious knee injury that frequently affects young individuals active in soccer, alpine skiing, handball and basketball. Regardless of treatment, an ACL injury is ... -
Pretargeting agents and At-211-labeled effector molecules: Synthesis and preclinical evaluation for pretargeted alpha-radioimmunotherapy.
(2012-05-15)Targeted therapies are treatment regimens in which tumor specific substances incorporating some sort of cell-killing effect are administered to patients. For cancer therapy they have emerged as a means of preventing ... -
Prevention and treatment of acute kidney injury after cardiac surgery
(2010-06-01)Acute kidney injury (AKI) occurs frequently after cardiac surgery and is independently associated with increased mortality. The main cause of AKI in these patients is renal ischemia. However, data on the renal oxygenation, ... -
Primordial radionuclides in pit lakes in Sweden
(2020-05-07)In Sweden, there are many pit lakes, originating from limestone quarries and metal mines, with unknown status in regard to the activity concentration of radionuclides. Such knowledge is generally available only for pit ... -
Principles of scaffold generation for bioengineering of the ovary and uterus: a study focusing on decellularization
(2021-05-27)Introduction: Cancer therapy often result in fertility problems due to inflicted injury to the reproductive organs. Since most women survive cancer, fertility preservation has become an important consideration during cancer ... -
Prognostic and predictive factors in colorectal cancer
(2009-02-06)Aim: The aim of the thesis was to study prognostic and predictive factors in patients treated for colorectal cancer (CRC). Method: In paper I, a retrospective comparison was made between the patients treated in 1999 ... -
Prognostic factors and tumor treatments in hepatocellular cancer
(2019-03-04)Background: Hepatocellular carcinoma (HCC) is one of the most common causes of cancer-related death worldwide. Prognosis is related to tumor burden, liver function, and performance status as well as treatment factors. ... -
Prognostic impact of coronary microvascular funtion in patients with ischemic heart disease.
(2018-03-09)Background: Ischemic heart disease is the leading cause of death globally. Despite recent advances in interventional and medical therapies, survivors of myocardial infarction are at high risk of recurrent cardiovascular ... -
Promoting the Clinical Relevance of 3D Bioprinting
(2022-02-03)This thesis focuses on the development of methodologies enabling the reconstruction of autologous, functional, and long-term-stable cartilage-like tissue using 3D bioprinting technology and animal experiments. The stability, ...