Browsing Doctoral Theses / Doktorsavhandlingar Institutionen för kliniska vetenskaper by Title
Now showing items 260-279 of 634
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Influence of inflammation and of stage of lung development on the development of neonatal lung injury
(2010-11-26)Bronchopulmonary dysplasia (BPD) is a major cause of mortality and long-term morbidity in prematurely born infants. Pulmonary inflammation, and abnormal alveolar and vascular development of the lung are histological ... -
Influence of postoperative treatment, surface treatment and stem design on the outcome of primary total hip arthroplasty
(2009-05-20)Aims: The aim of this study was to investigate the influence of postoperative treatment, surface treatment and stem design on the outcome of primary Total Hip Arthroplasty. The main intention was to study anteverted femoral ... -
Inguinal Hernia after Urologic Surgery in Males with Special Reference to Radical Retropubic Prostatectomy. A Clinical, Epidemiological and Methodological Study
(2006-10-02)Background and aims: In 1996 the first report indicating that inguinal hernia (IH) was a complication to radical retropubic prostatectomy (RRP) was published. The main aims of this thesis were to further establish this ... -
Initiation of Protein Biosynthesis in Skeletal Muscles at Feeding
(2010-05-28)Background and aim. Artificial nutrition by intravenous feeding has for decades indicated less than optimal support of whole-body protein metabolism and balance during some treatment conditions. Therefore, the present ... -
Insights from combining Action Research and System Dynamics when facilitating change and improvement processes in healthcare
(2022-09-30)BACKGROUND Healthcare is a complex system with multi-professional staff and multiple patient care pathways. Time pressure and minimal margins for error makes it challenging to implement new policies or procedures, no ... -
Integrative genomic and survival analysis of breast tumors
(2012-11-14)With the continued accumulation of genomic data at ever increasing resolution the challenge ahead lies in reading out meaningful clinical/biological information form the data that can contribute to a better understanding ... -
International Outcomes of Total Hip Arthroplasty: Influence of Patient, Implant, and Surgical factors on Total Hip Arthroplasty Survivorship in Sweden, the US, and Australia
(2019-05-22)Abstract Background Hip osteoarthritis (OA) is debilitating disease resulting in pain, stiffness, and reduced physical function. Although total hip arthroplasty (THA) is a successful treatment for OA, some THAs require ... -
Intervertebral disc regeneration. Studies on stem cell niches and cell transplantation
(2010-11-08)Abstract Intervertebral disc regeneration Studies on stem cell niches and cell transplantation Helena Barreto Henriksson Gothenburg 2010 Low back pain is a common condition in the Western world and disc degeneration ... -
Intestinal adaption in response to Roux-en-Y gastric bypass surgery
(2015-11-12)ABSTRACT Background: Obesity is a condition with increasing prevalence that leads to morbidity, decreased quality of life and reduced life expectancy. The only effective evidence-based treatment is bariatric surgery. The ... -
Intestinal preservation for transplantation: translational approaches
(2019-11-13)Background: Intestinal preservation injury (IPI) may result in various degrees of mucosal damage, which may later favor bacterial translocation, post-reperfusion syndrome, and upregulation of alloreactivity. Experimental ... -
Intestinal transplantation. Experimental and clinical studies
(2010-01-11)Intestinal preservation-reperfusion injury may result in various degrees of mucosal injury. Interestingly, the preservation injury is similar when using the current preservation solutions, which are given as a intravascular ... -
Intravoxel incoherent motion modeling - Optimization of acquisition, analysis and tumor tissue characterization
(2018-09-13)Intravoxel incoherent motion (IVIM) analysis provides a means to obtain information on diffusion and perfusion from a single MRI sequence. The measurements are completely noninvasive and the results have been shown to be ... -
Invasive and Metastatic Properties of Advanced Prostate Cancer
(2009-05-15)Prostate cancer is initially androgen-dependent (AD) and therefore androgen deprivation therapy (ADT) is generally used to treat advanced prostate cancer. However, the long-term treatment effects are insufficient and over ... -
Invasive treatment for intermittent claudication - clinical outcomes and cost-effectiveness
(2020-04-01)Intermittent claudication (IC) is caused by obstructive arterial lesions and is characterized by effort-induced pain in the lower extremity, limiting walking distance, and reduced health-related quality of life (HRQoL). ... -
Isocapnic hyperventilation in anaesthesia practice. Clinical and experimental studies
(2018-01-30)Abstract Background: Isocapnic hyperventilation (IHV) has been shown to shorten recovery time after volatile anaesthesia by accelerating elimination of inhalational agents by increasing minute ventilation while maintaining ... -
Isolated regional perfusion for metastases of malignant melanoma - Clinical and experimental studies
(2013-10-25)Background: Isolated regional perfusion is a treatment option mainly for localized metastatic disease. The principle idea is to surgically isolate a region of the body and connect the circulation to a heart-lung machine. ... -
Jejunal control of glucose homeostasis in the human body
(2021-11-15)Background: The prevalence of obesity and type-2 diabetes mellitus (T2DM) have risen dramatically over the last decades, and are major threats to the human health. Obesity, and also T2DM, is treated with lifestyle ... -
Kinematics and laxity in the knee, before and after Anterior Cruciate Ligament reconstruction. Evaluation using dynamic and static radiostereometric analysis
(2008-03-19)Introduction: Whether full active and passive extension training, started immediately after an Anterior Cruciate Ligament (ACL) reconstruction, will increase the post-operative A-P laxity of the knee has been the subject ... -
Kinesiophobia : various aspects of moving with musculoskeletal pain
(2006)Aim: The overall aim of this thesis was to investigate various aspects of the phenomenon of kinesiophobia among patients with musculoskeletal pain. Study population: For the purpose of this thesis 1304 patients, with ... -
Knee ligament injuries in male professional football players
(2019-10-25)ABSTRACT Knee ligament injuries are common in professional football and entail a significant time loss from football, but studies of knee ligament injuries other than anterior cruciate ligament (ACL) injuries are ...