Browsing Doctoral Theses / Doktorsavhandlingar Institutionen för kliniska vetenskaper by Title
Now showing items 197-216 of 631
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Experiences of living with cleft lip and palate - a gender perspective
(2021-11-10)The primary aim of this thesis was to investigate the influence of gender on the CL/P population with regard to treatment, self-reported appearance, psychosocial adjustment, and subjective experiences. Study I, a retrospective ... -
Experimental and population-based studies on colorectal cancer - Thymidine phosphorylase as a potential biomarker
(2014-09-05)Background: Colorectal cancer (CRC) is one of the most common malignancies, and the only reliable treatment option for cure is surgery. Method: Quantitative real-time polymerase chain reaction was used to analyze the ... -
Experimental Models of the Human Peritoneal Environment: Effects of TGF-beta and Hyaluronan
(2008-04-04)BACKGROUND Post surgical adhesion formation is still an unsolved problem and occurs when there is an imbalance between fibrin deposition and fibrin clearing capacity in the abdominal cavity. Transforming growth factor ... -
Experimental models with specific approaches to augment human fetal liver cell engraftment
(2014-05-27)Experimental models with specific approaches to augment human fetal liver cell engraftment Pradeep Patil Department of Surgery, Institute of Clinical Sciences, Sahlgrenska Academy at University of Gothenburg Background: ... -
Experimental studies on ovarian cryopreservation and transplantation
(2011-05-09)Around 8% of all cancer victims are below 40 years of age and the survival after cancer treatment during childhood and reproductive years has increased considerably to be around 80% today. The clinical field of fertility ... -
Exploring mechanisms of insulin secretion regulators using C. elegans
(2022-11-09)Diabetes mellitus is a group of disorders characterized by disrupted glucose homeostasis. Diabetes is one of the most dangerous diseases worldwide since it affects currently more than 500 million people. The pathogenesis ... -
Expression of Tissue Antigens in Human Pluripotent Stem Cells and Alterations During Differentiation
(2017-05-24)The major limiting factor in the treatment of patients with end-stage organ failure is the insufficient number of human organs available for transplantation. An unlimited access to human cells, tissues and organs would ... -
Extracellular matrix remodelling proteases in acute appendicitis and their impact on appendiceal perforation
(2010-04-21)Abstract Background Appendicitis is associated with varying degradation of extracellular matrix involved in tissue injury. The principal aim of this study was to investigate whether immunoreactive techniques could ... -
Factor V Leiden mutation and pregnancy. Haemostasis during pregnancy in non-carriers and carriers of factor V Leiden mutation, with special emphasis on placenta-mediated and venous thromboembolic complications and on blood coagulation and fibrinolysis markers for prediction of complications
(2009-10-12)Factor V Leiden (FVL) mutation elevates the risk of venous thromboembolism (VTE) in general. During pregnancy, the haemostatic balance is changed in the direction of hypercoagulability, resulting in an increased incidence ... -
Factors influencing women´s choice of contraception
(2011-05-26)Abstract Factors influencing women’s choice of contraception Ingela Lindh, Department of Obstetrics and Gynecology, Sahlgrenska Academy at the University of Gothenburg, Gothenburg Sweden Aims: To describe contraceptive ... -
Fast-track programs in total hip and knee replacement at Swedish hospitals - influences on safety, outcome and patients' experiences
(2020-04-14)ABSTRACT Background Fast-track is a care concept that aims to enhance recovery after surgery, resulting in shortened perioperative hospital stay. By using evidence-based methods in preparation and perioperative care ... -
Femoral shaft fractures in children and adolescents; stability, residual deformity and recovery of physical function
(2023-12-14)Femoral shaft fracture is the most common injury requiring hospital admission among children. The limited number of studies makes it challenging to provide accurate prognosis for recovery after femoral shaft fractures in ... -
Femoroacetabular Impingement Syndrome - Outcomes of Arthroscopic Hip Surgery
(2020-03-27)Hip and groin problems are common among young, active individuals. Femoroacetabular impingement (FAI) syndrome is an important cause of hip pain and reduced hip function among these patients. Bony abnormalities at the ... -
Femoroacetabular impingement syndrome. Trends and outcomes after arthroscopic treatment in the general and athlete population
(2021-08-18)Femoroacetabular impingement syndrome (FAIS) is a common cause of hip pain in the young and athletic population. The diagnosis - FAIS - is based on a triad of symptoms, clinical evaluation and radiographic signs. The ... -
Femoroacetabular Impingement: The Pursuit of Evidence
(2017-10-20)Femoroacetabular Impingement (FAI) is an important cause of hip pain in the young adult. It is the result of abnormal contact between the femoral head and neck junction and the acetabular rim. Although FAI has only recently ... -
Fetma och övervikt i barndomen - tidig identifiering av riskfaktorer
(2013-12-20)Background: The incidence of childhood obesity is increasing. Many children become obese during preschool years and stay obese, with lifelong health consequences, such as impaired insulin sensitivity. There is growing ... -
Folates in the treatment of colorectal cancer
(2015-05-11)ABSTRACT Folates in the Treatment of Colorectal Cancer Department of Surgery Institute of Clinical Sciences at Sahlgrenska Academy University of Gothenburg Helena Taflin Background: Colorectal cancer is one of the most ... -
Formation and repair of complex DNA damage induced by ionizing radiation
(2013-04-23)DNA is the critical target when cells are exposed to ionizing radiation, a potent stressor with capacity to produce complex DNA damages, thereby increasing the risk of cancer. DNA and associated histones form chromatin, ... -
Förbättrad radionuklidterapi av neuroblastom
(2023-04-26)Today, about half of the children diagnosed with high-risk neuroblastoma (HR-NB) survive due to considerable treatment improvements during the last decades. However, there is still much to be done for the other half who ... -
Functional outcome and experiences concerning daily life after malunion of the distal radius and corrective osteotomy
(2020-11-25)BACKGROUND. Distal radius fractures are common injuries that occur at all ages. The commonest complication is that the fracture heals in malunion. This can negatively affect function and the ability to perform activities. ...