Browsing Doctoral Theses / Doktorsavhandlingar Institutionen för kliniska vetenskaper by Title
Now showing items 422-441 of 628
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Paediatric sleep-disordered breathing - diagnostics and treatment
(2018-01-17)Sleep-disordered breathing (SDB) in children causes multiple health problems and diminished quality of life. It is usually caused by tonsil and adenoid hypertrophy and is traditionally treated with adenotonsillar surgery. ... -
Pain in Osteoarthritic Joints: Biological Signaling and 3D Models based on Imaging
(2019-12-19)Osteoarthritis (OA) is the most common joint disease, causing disability in middle-aged and elderly patients worldwide and imposing a huge socioeconomic burden. OA of the knee joint is a major cause of joint pain and, along ... -
Pancreatic Cancer. Experimental and Clinical Studies
(2013-09-20)Background: Pancreatic cancer is one of the most lethal of known cancers and the only treatment with possibility of cure is surgery. The costs associated with treatment of pancreatic cancer are reputably high, both in terms ... -
Patient-reported outcome measure and health-economic aspects of total hip arthroplasty. A study of the Swedish Hip Arthroplasty Register.
(2010-11-22)The Swedish Hip Arthroplasty Registry collects prospective, observational, nationwide data on all total hip arthroplasties (THAs) in Sweden. Implant survival has been the most commonly reported outcome variable. However, ... -
Patient-reported outcomes in children and adolescents born with esophageal atresia - condition-specific aspects of health-related quality of life and coping
(2017-03-17)Background: Survival rates in children with esophageal atresia (EA) have reached 90-95%, but they are at risk of chronic morbidity, mainly related to esophageal and respiratory dysfunction. Knowledge of condition-specific ... -
Patients' perceived outcomes in tetraplegia hand surgery
(2013-02-08)Aim: To investigate patients perceived benefits after upper limb surgery in persons with tetraplegia - with a special focus on the participants’ perspective and their experiences from regaining lost functions. Methods: A ... -
Patients' perspective on obesity surgery - expectations, experiences and self-reported outcomes
(2013-04-29)Overweight and obesity constitute a major challenge to human health worldwide, involving over 1.4 billion people. In Sweden, more than a third (36%) of the population is overweight, and 13% are obese. For the vast majority ... -
Pediatric Autoinflammatory Diseases: Conceptual, Clinical, and Mechanistic Dimensions
(2015-09-10)This thesis focuses on three paediatric autoinflammatory diseases in Sweden today; familial Mediterranean fever (FMF), periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis (PFAPA) and synovitis, acne, ... -
Pelvic floor dysfunction in nulliparous women
(2022-01-18)Background: Pelvic floor dysfunction (PFD) is a public health problem affecting millions of women worldwide. In addition to personal suffering, it also creates an economic burden for health care systems and society. Parity ... -
Periarticular changes in association with osteoarthritis in the hip, knee or shoulder
(2021-10-08)The aim of this thesis was to evaluate the presence of degenerative changes in the periarticular tendons in association with osteoarthritis (OA) in the hip, knee or shoulder. Moreover, changes in bone mineral density (BMD) ... -
Perinatal brain damage-phagoptosis and neuroprotection
(2024-03-27)Background: Neonatal encephalopathy is a serious outcome in term infants affecting 1-2/1000 live births and is often caused by perinatal hypoxia-ischemia (HI). However, brain injury is multifactorial and infection in the ... -
Perinatal essential fatty acid deficiency in mice: effects on metabolism and behaviour
(2011-05-09)Maternal nutritional status during pregnancy and lactation influences the health of the adult offspring and an adequate supply of essential fatty acids is important for foetal and postnatal growth and development. The ... -
Periprosthetic femoral fracture after total hip replacement. Incidence, risk factors, and treatment
(2020-02-18)This thesis investigates the incidence of surgically treated periprosthetic femoral fractures (PPFF) in Sweden between 2001 and 2011, the demography of this population, risk factors that may contribute to its occurrence ... -
Peritoneal fibrinolysis during pneumoperitoneum and laparoscopic surgery
(2007-11-23)BACKGROUND Laparoscopic surgery is believed to induce less postoperative adhesion formation compared with open procedures, but information regarding biological impact of a laparoscopic approach is limited. MATERIAL & ... -
Person-centred prehabilitation program to improve functioning
(2018-12-13)Introduction: Low back pain is a frequently reported symptom and has turned into a global problem. For people with severe chronic low back pain, spinal fusion surgery can be a treatment option. The outcome of fusion ... -
Pharmacokinetics and dosimetry in intraperitoneal radioimmunotherapy with 211At
(2014-03-24)The prognosis for patients diagnosed with disseminated cancer is often poor. Radioimmunotherapy (RIT) is a new approach to treat disseminated disease. The aim is to target tumor cells with monoclonal antibodies (mAbs) ... -
Photdynamic therapy for treatment of Acne Vulgaris in clinical studies; dose response and mode of action
(2009-04-30)This thesis deals with the use of photodynamic therapy (PDT) for treatment of Acne Vulgaris. Acne Vulgaris is one of the most common skin disorders. Conventional treatments target the pathogenic factors and include a variety ... -
Photodynamic therapy- pain and aspects of pain relief
(2011-11-28)Photodynamic therapy – pain and aspects of pain relief Christina Halldin Department of Dermatology and Venereology, Sahlgrenska University Hospital, Institute ... -
Physical Exercise in Cystic Fibrosis -studies on muscle strength, oxygen uptake and lung function in young adult patients
(2008-08-12)Muscular strength, lung function and exercise capacity are internationally reported to be markedly impaired in adult patients with cystic fibrosis (CF). Since 20 years physical exercise is one important part in the treatment ... -
Polycystic ovary syndrome - morphologic and dynamic evaluation by magnetic resonance imaging
(2013-05-10)Polycystic ovary syndrome (PCOS) is a complex endocrine disorder, affecting up to 15% of women of reproductive age. The syndrome is characterized by oligo-anovulation, hyperandrogenism and polycystic ovaries. What constitutes ...