Browsing Doctoral Theses / Doktorsavhandlingar Institutionen för kliniska vetenskaper by Title
Now showing items 58-77 of 631
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Barnfetma och Metabola Syndromet hos förskolebarn - tidiga faktorer och identifiering av riskindivider från ett longitudinellt perspektiv
(2019-02-15)Background: Overweight and obesity have increased worldwide and affect children at ever younger ages, resulting in cardiovascular disease and type 2 diabetes even in adolescents. This illustrates the importance of identifying ... -
Barretts esophagus - aspects on early detection of malignant transformation
(2016-10-20)Background: Barrett’s esophagus (BE) is a metaplastic mucosal transformation adjacent to the gastroesophageal junction, due to chronic reflux of gastric juices. BE is associated to an increased risk of esophageal adenocarcinoma ... -
Basal cell carcinoma: real-life burden on healthcare and simplified destructive treatments
(2023-10-18)Basal cell carcinoma (BCC) is the most common cancer in humans. With steadily increasing incidence rates, there is a constant need to evaluate current diagnostic methods and treatment alternatives to achieve effective care ... -
Being a Pediatric Oncologist: A Nationwide Study of Personal Resources and Difficulties When Working with Children with Cancer
(2010-08-30)Being a pediatric oncologist involves facing medical challenges, life-threatening conditions, psychosocial issues and existential provocation. The first nationwide study of 90 Swedish pediatric oncologists focuses on the ... -
Benefits and risks with digital dermoscopy and teledermoscopy
(2017-11-16)The increasing incidence of malignant melanoma and non-melanoma skin cancer (NMSC) makes it necessary to optimize the management of patients with suspicious skin lesions, from triaging, to establishing a diagnosis and ... -
Bio-psychosocial analyses of acute and chronic pain, especially in the spine - the effect of distress on pain intensity and disability.
(2011-05-26)The overall purpose was to assess factors that influence the experience of pain and disability due to acute low back pain (LBP) and chronic musculoskeletal pain (CMP). A further purpose was to outline the conceptual framework ... -
Bioabsorbable Screws for Pelvic Osteotomies in Children
(2022-01-07)Multiple conditions, with developmental dysplasia of the hip being a prime example, affect the congruity of the pediatric hip joint. A Salter osteotomy (SO) or a triple pelvic osteotomy (TPO) can be used to address suboptimal ... -
Biochemical and genetic markers after subarachnoid haemorrhage
(2015-09-28)ABSTRACT Background: Subarachnoid haemorrhage is a devastating disease with high morbidity and mortality despite novel treatment options are available. There are no established methods to measure the brain damage occurring ... -
Biochemical studies of carbohydrate blood group antigens - Carbohydrate phenotype in relation to cellular glycosyltranferases.
(2009-05-15)The possibility to alter the cell surface carbohydrate expression by insertion or deletion of glycosyltransferase genes is a powerful technique to study the biological function of selected carbohydrate antigens. However, ... -
Biodegradable magnesium implants, immunomodulation, and tissue repair/regeneration
(2023-10-26)The century-old paradigm of holding fractures with a metallic implant to enable bone repair, known as osteosynthesis, is still used today without alteration. Patients are increasingly being treated with metallic implants ... -
Biomarker discovery and assessment for prediction of kidney response after 177Lu-octreotate therapy
(2014-11-28)Patients suffering from neuroendocrine tumors are oftentimes presented with spread disease at the time of diagnosis. Therapy using somatostatin analogs is today the only potentially curative treatment option for these ... -
Biomarkers in mid-trimester amniotic fluid in relation to gestational duration and spontaneous preterm delivery
(2020-05-15)Background: The biological mechanisms and physiological pathways of pregnancy maintenance and timing of delivery are complex and multifactorial. Pregnancy clocks, partly controlled by timing mechanisms linked to fetal ... -
Biomechanical studies of finger extension function. Analysis with a new force measuring device and ultrasound examination in rheumatoid arthritis and healhty muscles
(2008-11-24)Aims: The overall aim of this thesis was to further our understanding of extensor muscles and their role for hand function. The aims of the studies were: To develop and evaluate a new device for finger extensor force ... -
Bladder pain syndrome/interstitial cystitis. Studies on classic BPS/IC, ESSIC type 3C, with special reference to the role of nitric oxide
(2012-11-09)Patients presenting with symptoms of Bladder Pain Syndrome (BPS) are challenging to the urologist. Previously known as Interstitial Cystitis (IC), this syndrome has been extensively debated and investigated. IC mainly ... -
Bladder Pain Syndrome/Interstitial cystitis: aspects on outcome after intravesical and surgical treatment
(2010-11-08)Background BPS/IC is a chronic syndrome with bladder pain, divided into two main types: one with so called Hunner`s lesions (classic type) and one without (nonulcer type). In the recently presented ESSIC classification ... -
Blås och tarmdysfunktion hos barn med anorektala missbildningar
(2013-10-15)Background: Bowel dysfunction is seen in all children with anorectal malformations (ARMs) and is strongly related to associated anomalies commonly found in these patients. The presence of a megarectosigmoid (MRS) further ... -
Blood pressure-dependent changes in plasma volume, glycocalyx and platelet function during anaesthesia -Clinical and experimental studies
(2021-05-11)Background: Worldwide, more than 300 million surgeries are performed each year. General anaesthesia provides the surgical patient with a state of controlled loss of sensation and awareness. It is common that general ... -
Bone and Cartilage Regeneration: Wnt Signaling Pathway in Healing
(2014-02-10)The Wnt signaling pathway plays a central role in bone and cartilage embryonic development, processes that are recapitulated during regeneration. Imbalance in such well conserved and complex system often contributes to ... -
Bone and fat tissue in children and adolescents: studies with focus on osteocalcin
(2016-09-15)The general AIM was to investigate the possible interplay between bone and fat tissue through clinical studies of children and adolescents. Osteocalcin (OC), a bone formation marker, has been proposed to act as a link ... -
Bone health and nutrition treatment. Studies on young women with anorexia nervosa and children with epilepsy
(2023-08-17)Background: Adequate nutritional status is crucial for optimal longitudinal growth and accrual of bone mass during childhood and adolescence. Peak bone mass achieved in young adulthood affects bone health throughout life. ...