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Adaptation and Protein Quality Control Under Metalloid Stress
(2015-04-22)
Toxic metals and metalloids are emerging as major environmental pollutants, having ecological consequences as well as being linked to a broad range of degenerative conditions in animals, plants and humans. While the toxicity ...
Regulation and transport mechanisms of eukaryotic aquaporins
(2013-01-11)
Aquaporins are found in all kingdoms of life where they are involved in water homeostasis. They are small transmembrane water conducting channels that belong to the ancient protein family Major Intrinsic Proteins (MIP). ...
Cellular Responses to Arsenite and Cadmium - Mechanisms of Toxicity and Defense in Saccharomyces cerevisiae
(2016-05-12)
All biological systems have to cope with a wide range of metals that are present in the environment. Metals can be essential or beneficial for life, inert or non-essential and toxic, often depending on their chemical form ...
Toxic Metals and Proteostasis – Molecular mechanisms of arsenite and cadmium-induced protein aggregation in Saccharomyces cerevisiae
(2024-04-16)
Cadmium and arsenite are common environmental pollutants; considered highly toxic and pose a substantial threat to human health with millions of people worldwide being at risk of exposure. Cadmium and arsenite are carcinogenic ...