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Atmospheric Chemistry of Volatile Organic Compounds: Oxidation Products, Mechanisms and Secondary Organic Aerosol Formation
(2019-01-15)
The results from this work are a piece in understanding the complex puzzle of atmospheric
aerosol formation. Secondary organic aerosol (SOA) formed by the oxidation
of volatile organic compounds (VOC) in the atmosphere ...
Conformational Flexibility in Protein Function: Dynamics of S100A4, Photosynthetic Reaction Centre and the Prenylating Enzymes UbiA and MenA
(2014-09-11)
Proteins are the most versatile macromolecules and they are essentially involved in the biological processes throughout all living organisms. The three dimensional structure of proteins and their dynamical properties ...
On aging and the role of Ubp3 in heterochromatic gene silencing and protein quality control
(2014-09-04)
Aging is characterized by a build-up of damage in organisms ranging from protists to multi-cellular species. This damage adversely affects core components such as DNA and proteins which are necessary to sustain life. ...
Development of novel serotonin 5-HT6 and dopamine D2 receptor ligands and MAO A inhibitors - Synthesis, structure-activity relationships and pharmacological characterization
(2013-09-05)
It is known since the 1950s that enhancement of the levels of the monoamines dopamine (DA), serotonin (5-hydroxytryptamine, 5-HT) and norepinephrine (NE) in the brain will relieve the symptoms of major depression, and ...
Structural Features of Bacteriophytochromes. Photoactivated Proteins studied by Serial Femtosecond Crystallography
(2018-03-22)
The key to life on earth is sunlight, which reaches the planet as an energy source.
Nature has evolved different types of photoreceptor proteins to detect optimal light
conditions for biochemical processes. A type of red ...
Lipidic Cubic Phase Microcrystallization and its Application in Serial Crystallography
(2020-10-23)
Every living organism contain a cell membrane which is an important cell structure with a vast variety of different functions such as cell signaling, transportation and energy production. One of the most important functions ...
Electrochemical and microscopic analysis of chemical signalling in biological systems
(2019-10-01)
Cellular communication is a prerequisite in multicellular organisms in order to survive. Many times, this communication occurs through the highly controlled and regulated release of chemical signals through a process known ...
Adaptation and Protein Quality Control Under Metalloid Stress
(2015-04-22)
Toxic metals and metalloids are emerging as major environmental pollutants, having ecological consequences as well as being linked to a broad range of degenerative conditions in animals, plants and humans. While the toxicity ...
Using Light to Regulate the Activity of RET Kinase: Design, synthesis and evaluation of photoswitchable DFG-out RET kinase inhibitors
(2021-08-26)
Protein kinases are essential for signal transduction and regulate most cellular processes, such as metabolism, membrane transport, motility, and cell cycle. Although they play a critical role in cells and have a strong ...
Nanoparticles from shipping and road traffic
(2015-05-07)
In the urban environment road traffic is the dominant source of aerosol particles while in
coastal and harbour areas shipping is also a significant source. For shipping there are no direct
regulations regarding particle ...