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Secondary Organic Aerosols: Composition, Gas-to-Particle Partitioning and Physical Properties
(2019-02-21)
Atmospheric aerosols influence our climate and air quality. Aerosol particles in the
atmosphere are transformed through many different physical and chemical reactions. A
substantial fraction of the particles in the ...
Synthesis, Pharmacological Characterization and QSAR Modelling of 4-Phenylpiperidines and 4-Phenylpiperazines Effects on the dopaminergic neurotransmission in vivo
(2012-11-19)
The endogenous neurotransmitter dopamine (DA) is involved in several functions that are controlled from the central nervous system (CNS), for example behaviour, memory, cognition and reward. A disturbed dopaminergic ...
Electrochemical and microscopic analysis of chemical signalling in biological systems
(2019-10-01)
Cellular communication is a prerequisite in multicellular organisms in order to survive. Many times, this communication occurs through the highly controlled and regulated release of chemical signals through a process known ...
Molecular biology of barnacle Balanus improvisus settlement
(2019-09-13)
The aim of this thesis was to investigate molecular mechanisms of various aspects of barnacle settlement, using the acorn barnacle Balanus improvisus. This barnacle is a common fouling species and a model organism for ...
Characterization of Amino Acid tRNA Ligases using the Analytical Ultracentrifuge
(2015-09-09)
ABSTRACT.
Quaternary structures of amino acid tRNA ligases/synthetases (aaRS) in the native as well as in denatured forms were examined by molecular weight determinations (paper I-IV). Analytical ultracentrifugation, ...
Time Resolved Diffraction Studies of Structural Changes in Sensory Rhodopsin
(2019-11-29)
Responding to different light conditions is an essential process for
many organisms on earth. Unicellular organisms are no exception to this and
mechanisms for controlling cellular movement must often be sensitive ...
The Extended Role of the Molecular Chaperone CCT
(2016-03-23)
The oligomeric chaperone CCT is a large ATP-dependent chaperonin that consists of two
rings placed back-to-back with eight different paralogous subunits with a size of ~ 55 kDa
that sit in each of the two rings. The ...
Determine the developmental dynamics of primordial follicles in the mouse ovary
(2014-04-15)
Ovarian follicles are the basic functional units of the mammalian ovary. Progressive activation of primordial follicles serves as the source of fertilizable ova. In this thesis, by generating the Foxl2-CreERT2 and ...
Structural analyses of immune cell receptor signalling and activation
(2013-04-17)
Structural biology is a scientific field where the aim is to observe macromolecules on a atomic level to understand their functions. Often these macromolecules are proteins that make, almost, everything happen within the ...
Regulation and transport mechanisms of eukaryotic aquaporins
(2013-01-11)
Aquaporins are found in all kingdoms of life where they are involved in water homeostasis. They are small transmembrane water conducting channels that belong to the ancient protein family Major Intrinsic Proteins (MIP). ...