Browsing Doctoral Theses / Doktorsavhandlingar Institutionen för kemi och molekylärbiologi by Title
Now showing items 69-88 of 205
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Formation and Distribution of Marine Biogenic Halocarbons with Emphasis on Polar Regions
(2012-10-19)It is well-established that marine micro- and macroalgae form volatile halogenated compounds (halocarbons). Production occurs throughout the world ocean with strong regional sources in coastal areas. In the atmosphere, ... -
Formation and Transformation of Atmospheric Brown Carbon (BrC)
(2022-11-23)Atmospheric brown carbon (BrC) aerosol absorbs light in the UV-Vis spectrum and has poorly constrained but potentially large climate forcing impacts. Most current climate models lack detailed chemistry and interlinked ... -
Formation of small molecules in space through the process of radiative association
(2023-10-16)This thesis is dedicated to calculating the reaction rate constants for the formation of molecules through radiative association (RA) under interstellar conditions. The molecules that have been studied are CH, AlCl, Na+ ... -
Formation, ageing and thermal properties of secondary organic aerosol
(2013-02-07)In order to properly represent and predict the effects of aerosol in climate systems, an accurate description of their formation and properties is needed. This thesis describes work done to increase the knowledge of processes ... -
FoxF genes in development and disease
(2014-05-08)Forkhead transcription factors of the FoxF group are important during embryonic de-velopment, and mutation of either of the members, Foxf1 and Foxf2, has fatal conse-quences. In this thesis, I present our recent findings ... -
From Silica Nano-Particles to Silica Gels and Beyond - Salt Induced Aggregation of Silica Nano-Particles and the Stability of Resultant Gels
(2020-04-21)Aqueous silica nanoparticle suspensions are widely available and used within a number of industries. A relatively new area of application is as a grouting material for sealing narrow fractures in tunnels. While silica ... -
Functional details of human HtrA2 protease studied by NMR spectroscopy
(2022-11-24)Cells rely on an array of cellular machineries in the protein quality control system (PQC) to maintain the health of the collective proteome. The HtrA family of serine proteases are found in all kingdoms of life and function ... -
Functional roles of protein phase separated assemblies in cellular stress response and proteinopathies
(2022-11-09)For a long time, pertinent biological conundrums, such as the organization and compartmentalization of the cytoplasm and nucleoplasm, perplexed the scientific community. The organization of the complex biochemistry in an ... -
The Genetics of Adaptation and Evolvability in Yeast
(2022-10-18)Evolution is the hereditary change in life forms that has shaped the divergence of all organisms that inhabit planet Earth. I used the yeast Saccharomyces cerevisiae to study how adaptive evolution increases the fitness ... -
How ship exhaust particles change cloud activity
(2024-01-08)The Arctic is experiencing surface warming rates that exceed those observed at lower latitudes. This is caused by a complex system of feedback mechanisms in the Arctic climate system and is referred to as Arctic ... -
Human Aquaporins: Production, Characterization and Interactions
(2015-11-06)Membrane proteins are essential components of the cell and responsible for the communication with the outside environment and transport of molecules across the membrane. Water transport is facilitated by aquaporins, which ... -
Hydrous iridium oxide for in-situ pH sensing: electrodeposition, properties and applications.
(2013-05-20)For heterogeneous processes, such as electrochemical reactions taking place at an elec- trode, the chemical conditions at the reaction interface can differ significantly from the bulk. Consumption of reactants leads to ... -
Identification of novel BRCA2-binding proteins that are essential for meiotic homologous recombination
(2021-01-27)Meiotic recombination is a molecular process in which the induction and repair of programmed DNA double-strand breaks (DSBs) creates genetic exchange between homologous chromosomes and thus increases genetic diversity and ... -
Implementation and development of serial synchrotron crystallography at MAX IV
(2023-10-11)Over the past decade, remarkable advancements in femtosecond X-ray free-electron lasers (XFELs) have brought about a profound transformation in structural biology. These XFELs have opened up exciting opportunities for ... -
Improving integration efficiency and precision of CRISPR/Cas9-mediated genome editing
(2023-09-07)The clustered regularly interspaced short palindromic repeats (CRISPR) – CRISPR-associated protein 9 (Cas9) system has revolutionized the field of genome engineering, providing a cost-effective and fast tool for targeted ... -
Inhibition of the MDM2/p53 Interaction Design, Synthesis and Evaluation of MDM2 Inhibitors
(2015-02-20)Numerous essential cellular processes are regulated by protein-protein interactions (PPIs) and PPIs have therefore been recognised as potential new drug targets. The transcription factor p53 is often referred to as the ... -
Inhibition of the mevalonate pathway in C. elegans: Consequences and implications
(2015-09-15)The mevalonate pathway in human is responsible for the synthesis of cholesterol and other important biomolecules such as coenzyme Q (a component of the electron transport chain in mitochondria), dolichols (important for ... -
Integrative analysis of osmoregulation in yeast Saccharomyces cerevisiae
(2014-05-06)Similar to other unicellular organisms, yeasts frequently encounter environmental stress such as heat shock, osmotic stress, and nutrition limitations, which challenge their growth potential. To survive, all living cells ... -
Interaction of Natural Organic Matter molecules with TiO2 nanoparticles: An Experimental Adsorption and Aggregation study
(2018-08-16)Mechanisms by which synthetic nanoparticles are released into natural environments and the potential impact of nanoparticles on living organisms have been discussed frequently over the past decade. Interactions of nanoparticles ... -
Interrogation of Biological Samples by ToF-SIMS using New Primary Ion Beams and Sample Preparation Methods
(2017-01-12)Mass spectrometry is a very versatile and important technique in analytical chemistry. From atomic bombs to Alzheimer’s disease, after a century of improvements and developments there are now countless applications for ...