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Predicting functional upstream open reading frames in Saccharomyces cerevisiae

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Title: Predicting functional upstream open reading frames in Saccharomyces cerevisiae
Authors: Selpi
Bryant, Christopher H
Kemp, Graham JL
Sarv, Janeli
Kristiansson, Erik
Sunnerhagen, Per
Issue Date: 30-Dec-2009
Publication type: article, peer reviewed scientific
Organization: Department of Mathematical Sciences, Chalmers University of Technology and the University of Gothenburg
Department of Zoology, University of Gothenburg
Department of Cell and Molecular Biology, Lundberg Laboratory, University of Gothenburg
Citation: BMC Bioinformatics. 2009 Dec 30;10(1):451
Abstract: Abstract Background Some upstream open reading frames (uORFs) regulate gene expression (i.e., they are functional) and can play key roles in keeping organisms healthy. However, how uORFs are involved in gene regulation is not yet fully understood. In order to get a complete view of how uORFs are involved in gene regulation, it is expected that a large number of experimentally verified functional uORFs are needed. Unfortunately, wet-experiments to verify that uORFs are functional are expensive. R... more
ISSN: 1471-2105
Description: © 2009 Selpi et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Appears in Collections:Articles / Artiklar Institutionen för matematiska vetenskaper



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