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Discovery of microvascular miRNAs using public gene expression data: miR-145 is expressed in pericytes and is a regulator of Fli1


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Title: Discovery of microvascular miRNAs using public gene expression data: miR-145 is expressed in pericytes and is a regulator of Fli1
Authors: Larsson, Erik
Fredlund Fuchs, Peder
Heldin, Johan
Barkefors, Irmeli
Bondjers, Cecilia
Genove, Guillem
Arrondel, Christelle
Gerwins, Pär
Kurschat, Christine
Schermer, Bernhard
Benzing, Thomas
Harvey, Scott J
Kreuger, Johan
Lindahl, Per
Issue Date: 16-Nov-2009
Publication type: article, peer reviewed scientific
Organization: Institute of Biomedicine, University of Gothenburg, SE-405 30 Gothenburg, Sweden
Citation: Genome Medicine. 2009 Nov 16;1(11):108
Abstract: Abstract Background A function for the microRNA (miRNA) pathway in vascular development and angiogenesis has been firmly established. miRNAs with selective expression in the vasculature are attractive as possible targets in miRNA-based therapies. However, little is known about the expression of miRNAs in microvessels in vivo. Here, we identified candidate microvascular-selective miRNAs by screening public miRNA expression datasets. Methods Bioinformatics predictions of microvascular-selective ex... more
ISBN: http://dx.doi.org/10.1186/gm108
ISSN: 1756-994X
Description: © 2009 Larsson et al.; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
URI: http://hdl.handle.net/2077/28470
Appears in Collections:Articles / Institute of Biomedicine

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