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Regulatory CD4+FOXP3+ T cells in Helicobacter pylori-induced disease
(2009-10-01)
Helicobacter pylori colonize the gastric or duodenal mucosa of approximately half of the worlds’ population. Although most individuals are asymptomatic, H. pylori infection cause peptic ulcers or gastric cancer in 10-15 % ...
Multi-level characterization of host and pathogen in Helicobacter pylori-associated gastric carcinogenesis
(2014-11-06)
Today, more than half of the world’s population is infected with Helicobacter pylori, and two to three per cent of these will develop gastric cancer associated with this infection. Gastric cancer is today the third largest ...
Glycan dependent Helicobacter spp. and Streptococcus oralis binding to mucins in the gastric and oral mucosal niches
(2021-03-26)
Helicobacter pylori infects the stomach of half of the world’s population, while Helicobacter suis colonizes pigs and is the most common non-H. pylori Helicobacter species that also infects human stomach. Infection with ...
Recombinant mucin-type proteins as tools for studies on the interactions between Helicobacter pylori and its carbohydrate receptors
(2020-06-11)
Glycan-protein interactions are important in pathogen adhesion and infections. H. pylori has adhesins which enables it to bind to glycans on the gastric mucosa and, in the long run, cause gastric cancer. The reported current ...
Humoral and cellular immune response to Helicobacter pylori in Bangladeshi children and adults that may be related to protection
(2010-01-26)
Helicobacter pylori (Hp) colonizes the human gastric and duodenal mucosa and the infection may cause peptic ulcers and gastric adenocarcinoma. Half of the world’s population is infected with Hp with the highest prevalence ...
Function of natural killer cells in Helicobacter pylori infection and gastric cancer
(2011-02-22)
Helicobacter pylori infection is one of the most wide-spread infections in the world and causes a chronic inflammation in the gastrointestinal mucosa characterised by increased production of IFN-γ and is associated with ...
LEUKOCYTE RECRUITMENT TO HUMAN GASTROINTESTINAL TISSUES - STUDIES IN H. PYLORI-INDUCED GASTRITIS AND COLON ADENOCARCINOMAS
(2010-11-19)
Chronic inflammation is a major pathological basis for tumor development and two examples are H. pylori infection of the stomach mucosa and inflammatory bowel disease, which are strongly associated with gastric and colon ...
The role of IL-17A and IFNγ in vaccine-induced protection against Helicobacter pylori
(2013-11-22)
It is estimated that half the world’s population is infected with Helicobacter pylori in the stomach. Chronic H. pylori infection can lead to peptic ulcer disease or gastric cancer, but only in a sub-population of infected ...