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Studies on the Expression and Regulation of Enterotoxins and Colonization Factors in Enterotoxigenic Escherichia coli (ETEC)
(2008-02-28)
Enterotoxigenic Escherichia coli (ETEC) is one of the most common causes of acute watery diarrhoea in developing countries, particularly among local children less than five years and is also the most common cause of diarrhoea ...
Epidemiology, molecular characterisation and toxin regulation of enterotoxigenic Escherichia coli (ETEC) isolated from children with diarrhoea
(2013-05-22)
Acute diarrhoeal diseases are among the major causes of morbidity and mortality in children under 5 years of age in developing countries. Knowledge of the epidemiology of such diseases and the causative agents is important ...
Whole Genome Sequencing of Enterotoxigenic Escherichia coli
(2016-05-06)
Enterotoxigenic Escherichia coli (ETEC) infections are a common cause of diarrhea but little is known about the evolution and genomic composition of ETEC. The main aim of this thesis was to generate a large collection of ...
Vaccination against cholera and ETEC diarrhea and interventions to improve vaccine immune responses.
(2009-06-10)
Vaccination against cholera and ETEC diarrhea and interventions to improve vaccine immune
responses
Abstract
Vibrio cholerae O1 and enterotoxigenic Escherichia coli (ETEC) together account for the majority of bacterial ...
Mucus and mucins during gastrointestinal infections
(2014-03-24)
The gastrointestinal tract is protected by a continuously secreted mucus layer formed by mucin glycoproteins. The mucus layer and mucins change dynamically during infection. The main focus of this thesis was to investigate ...
Genetic diversity of the heat labile (LT) and heat stable (ST) toxins of human enterotoxigenic Escherichia coli (ETEC): New insights into polymorphism, regulation, and gene transcription
(2015-09-16)
Infection with enterotoxigenic Escherichia coli (ETEC) is a leading cause of diarrhea in children in developing countries and travelers to endemic regions. ETEC is a diverse pathogen, with a wide range of virulence factors ...
Approaches to Enhance and Evaluate the Immunogenicity of an Oral ETEC Vaccine
(2015-11-05)
Enterotoxigenic Escherichia coli (ETEC) is a major cause of childhood diarrhoea in the
developing world and the most common cause of travellers’ diarrhoea. A new oral
multivalent ETEC vaccine (MEV) containing killed ...
Presence and viability of enterotoxigenic Escherichia coli (ETEC) in aquatic environments
(2009-12-07)
Enterotoxigenic Escherichia coli (ETEC) is one of the major causes of diarrhoea among children in developing countries and in travelers to these regions. The bacteria are spread via contaminated water and food, and surface ...
Structural analyses of carbohydrate receptors for enterotoxins and adhesins of enterotoxigenic Escherichia coli
(2023-11-10)
Carbohydrate-binding proteins expressed by microbes are key determinants in initiating
and sustaining infections that account for millions of deaths each year. This thesis fo-
cused on proteins integral to infections ...