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Lack of effect of apolipoprotein C3 polymorphisms on indices of liver steatosis, lipid profile and insulin resistance in obese Southern Europeans


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Title: Lack of effect of apolipoprotein C3 polymorphisms on indices of liver steatosis, lipid profile and insulin resistance in obese Southern Europeans
Authors: Sentinelli, Federica
Romeo, Stefano
Maglio, Cristina
Incani, Michela
Burza, Maria A
Scano, Francesca
Coccia, Federica
Cossu, Efisio
Leonetti, Frida
Baroni, Marco G
Issue Date: 10-Jun-2011
Publication type: article, peer reviewed scientific
Organization: University of Gothenburg, Department of Molecular and Clinical Medicine, Sahlgrenska Center for Cardiovascolar and Metabolic Research, Sweden
Citation: Lipids in Health and Disease. 2011 Jun 10;10(1):93
Abstract: Abstract Background Apolipoprotein C3 (APOC3) is a component of triglyceride-rich lipoproteins, and APOC3 rs2854116 and rs2854117 polymorphisms have been associated with non-alcoholic fatty liver disease, hypertriglyceridaemia, and insulin-resistance. Objective To determine if the APOC3 variants alter the susceptibility of obese subjects to develop liver damage, hypertrigliceridaemia, and insulin-resistance. Methods The study was carried out on 585 unrelated obese Italians (median body mass inde... more
Description: © 2011 Sentinelli et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited
URI: http://hdl.handle.net/2077/26362
Appears in Collections:Articles / Institute of Medicine

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