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Polymorphism, selection and tandem duplication of transferrin genes in Atlantic cod (Gadus morhua) - Conserved synteny between fish monolobal and tetrapod bilobal transferrin loci


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Title: Polymorphism, selection and tandem duplication of transferrin genes in Atlantic cod (Gadus morhua) - Conserved synteny between fish monolobal and tetrapod bilobal transferrin loci
Authors: Andersen, Øivind
De Rosa, Maria Cristina
Pirolli, Davide
Tooming-Klunderud, Ave
Petersen, Petra E
André, Carl
Issue Date: 25-May-2011
Publication type: article, peer reviewed scientific
Organization: Department of Marine Ecology-Tjärnö, Gothenburg University, S-45296 Strömstad, Sweden.
Citation: BMC Genetics. 2011 May 25;12(1):51
Abstract: Abstract Background The two homologous iron-binding lobes of transferrins are thought to have evolved by gene duplication of an ancestral monolobal form, but any conserved synteny between bilobal and monolobal transferrin loci remains unexplored. The important role played by transferrin in the resistance to invading pathogens makes this polymorphic gene a highly valuable candidate for studying adaptive divergence among local populations. Results The Atlantic cod genome was shown to harbour two t... more
ISBN: http://dx.doi.org/10.1186/1471-2156-12-51
ISSN: 1471-2156
Description: © 2011 Andersen et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
URI: http://hdl.handle.net/2077/25884
Appears in Collections:Articles / Department of Marine Ecology

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