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Evolutionary loss of 8-oxo-G repair components among eukaryotes


Please use this identifier to cite or link to this item: http://hdl.handle.net/2077/25282

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Title: Evolutionary loss of 8-oxo-G repair components among eukaryotes
Authors: Jansson, Kristina
Blomberg, Anders
Sunnerhagen, Per
Alm Rosenblad, Magnus
Issue Date: 1-Sep-2010
Publication type: article, peer reviewed scientific
Publisher: Genome Integrity 2010, 1:12
Organization: Department of Cell and Molecular Biology, Lundberg Laboratory, University of Gothenburg
Citation: Genome Integrity. 2010 Sep 01;1(1):12
Abstract: Abstract Background We have examined the phylogenetic pattern among eukaryotes of homologues of the E. coli 7,8-dihydro-8-oxoguanine (8-oxo-G) repair enzymes MutY, MutM, and MutT. Results These DNA repair enzymes are present in all large phylogenetic groups, with MutM homologues being the most universally conserved. All chordates and echinoderms were found to possess all three 8-oxo-G repair components. Likewise, the red and green algae examined have all three repair enzymes, while all land-livi... more
Description: © 2010 Jansson et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
URI: http://hdl.handle.net/2077/25282
Appears in Collections:Artiklar / Articles Department of Cell and Molecular Biology / Institutionen för cell- och molekylärbiologi

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