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Studies on bacterial transmission pathways in a high endemic area, with a focus on Helicobacter pylori

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Title: Studies on bacterial transmission pathways in a high endemic area, with a focus on Helicobacter pylori
Authors: Janzon, Anders
Issue Date: 29-Jun-2009
University: University of Gothenburg. Sahlgrenska Academy
Institution: Institute of Biomedicine. Department of Medical Microbiology and Immunology
Parts of work: I. Lothigius Å., Janzon A., Begum Y., Sjöling Å., Qadri F., Svennerholm A.-M. and Bölin I. Enterotoxigenic Escherichia coli is detectable in water samples from an endemic area by real-time PCR. Journal of Applied Microbiology 2008 104 (4):1128-1136.

II. Janzon A., Sjöling Å., Lothigius Å., Ahmed D., Qadri F. and Svennerholm A.-M. Failure To Detect Helicobacter pylori DNA in Drinking and Environmental Water in Dhaka, Bangladesh, Using Highly Sensitive Real-Time PCR Assays. Applied and Environmental Microbiology May 2009 75: 3039-3044.

III. Janzon A., Bhuiyan T., Lundgren A., Qadri F, Svennerholm A.-M. and Sjöling Å. Presence of high numbers of transcriptionally active Helicobacter pylori in vomitus from Bangladeshi patients suffering from acute gastroenteritis. Submitted manuscript

IV. Janzon A., Svennerholm A.-M. and Sjöling Å. Helicobacter pylori virulence gene expression in a mouse model. Unpublished manuscript
Date of Defence: 2009-06-09
Disputation: Tisdagen den 9 juni 2009, kl. 9.00, Hörsal Arvid Carlsson, Academicum, Medicinaregatan 3, Göteborg
Degree: Doctor of Philosophy (Medicine)
Publication type: Doctoral thesis
Keywords: H. pylori
enterotoxigenic E. coli
V. cholerae
real-time PCR
transmission pathways
mouse infection models
bacterial gene expression
Abstract: Even though half of the world’s population is infected with Helicobacter pylori, which causes gastritis, peptic ulcer and gastric cancer, the transmission routes of these bacteria remain unknown despite extensive epidemiological studies. Enterotoxigenic Escherichia coli (ETEC) and Vibrio cholerae are two of the most common causes of acute watery diarrhea in developing countries. The main aim of this thesis was to study transmission pathways of these bacteria, with a focus on H. pylori, through a... more
ISBN: 978-91-628-7815-3
Appears in Collections:Doctoral Theses from Sahlgrenska Academy
Doctoral Theses / Doktorsavhandlingar Institutionen för biomedicin
Doctoral Theses from University of Gothenburg / Doktorsavhandlingar från Göteborgs universitet



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