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Chronic Achilles tendon rupture - surgical reconstruction and post-operative outcomes
(2023-03-28)When the treatment of Achilles tendon ruptures is delayed by more than 4 weeks, the rupture is classified as chronic. This thesis aims to examine the postoperative outcome of chronic Achilles tendon ruptures treated ... -
lmproving Procedure Selection and Surgical Technique in Bariatric Surgery
(2023-03-28)Bariatric surgery is currently the most effective treatment for obesity and its metabolic comorbidities. There are, however, unexplored differences between surgical methods regarding outcomes and suitability for the ... -
Aspects of cardiac arrest in Sweden - studies based on the Swedish Registry for CPR
(2023-03-22)Background: Since the introduction of modern cardiopulmonary resuscitation (CPR) by Peter Safar in the late 1950s, a tremendous amount of work and scientific discovery has expanded our knowledge of cardiac arrest (CA), ... -
Priming and activation of neutrophils from blood and tissue
(2023-03-17)Inflammation is a powerful process, involved in many disease states, as well as in physiological situations. Neutrophils, the main characters of this thesis, are potent immune cells with the capacity to regulate inflammatory ... -
Diagnostic, Prognostic, and Disease Activity Biomarkers in Multiple Sclerosis
(2023-03-15)Multiple sclerosis (MS) is the most common immune-mediated disease of the central nervous system. While benign cases exist, if left untreated, MS results in the compounding accumulation of disability. In the last two ... -
Psoriatic arthritis: cardiovascular risk factors, health-related quality of life and effects of weight loss treatment
(2023-03-15)Background: Psoriatic arthritis (PsA) is an inflammatory rheumatic disease, characterized by arthritis, dactylitis, enthesitis and sometimes axial disease. PsA is associated with several comorbidities and reduced health-related ... -
Towards an item bank to measure patient-reported experience of person-centred care
(2023-03-03)The reorienting of healthcare towards a more person-centred approach requires new approaches to evaluate care from the patient perspective. The overall aim of this thesis was to explore care from the perspective of people ... -
Early identification of primary health care patients at risk of sick leave due to work-related stress
Aim: Work-related stress and sick leave are common among primary health care patients, and general practitioners (GPs) often handle cases involving stress and work capacity in their daily practices. This thesis aimed to ... -
Endometrial Cancer - Studies on recurrences, complications and preoperative diagnostics
(2023-02-27)Introduction: The most common gynecological cancer is Endometrial Cancer (EC). The prognosis is generally favorable, mainly due to an early diagnosis. However, there are subgroups of EC with a higher risk for metastases ... -
Arbetsskador och trafikskador: analys av historiska data
(GÖTEBORGS UNIVERSITET, 2023-02-25)Rapporten presenterar ett sätt att söka riskfaktorer för arbetsskador och trafik-skador i historiskt material. Korrelations- och regressionsanalyser har utförts med tidsserier av anmälda fall av arbetsskador och trafikskador, ... -
Association between polygenic risk scores and outcome of electroconvulsive therapy
(2022)Identifying biomarkers associated with response to electroconvulsive therapy (ECT) may aid clinical decisions. The authors examined whether greater polygenic liabilities for major depressive disorder, bipolar disorder, and ... -
The Predictive Value of Health Anxiety for Cancer Incidence and All-Cause Mortality: A 44-Year Observational Population Study of Women
(2021)Objective: Long-term data concerning mortality and serious illness as a function of health anxiety are scarce. We aimed to study health anxiety in relation to long-term mortality and cancer morbidity among women. Methods: ... -
Diagnosis, mortality and professional life in patients with heart failure
(2023-02-22)Background: Heart failure (HF) is a common and severe disease with an increasing incidence among young adults. An emerging composite endpoint is home-time. Little is known, on how living with HF affects professional life. ... -
Roles of Androgens in Cardiovascular Physiology and Pathophysiology
(2023-02-20)ABSTRACT Atherosclerosis is the major underlying cause of cardiovascular disease, such as myocardial infarction (MI) and stroke, and these conditions are the leading causes of death both in Sweden and globally. The ... -
Patient-derived scaffolds as a 3D model for breast cancer
(2023-02-17)Breast cancer is the most common cancer form in women worldwide. Many patients will have recurrent disease and more efficient targeted therapies are needed. The tumor microenvironment is a heterogenous complex mix of cells ... -
Translational genetics identifies a novel target to treat fatty liver disease
(2023-02-09)Fatty liver disease (FLD) is rapidly prevailing as the most common liver disease worldwide, with an estimated of one-quarter of the global population affected. Environmental and genetic determinants contribute to FLD ... -
Health economic aspects of stroke: stroke prevention and effects on spouses' healthcare consumption and income
(2023-01-23)The overall aim of this thesis was to investigate two health economic aspects of stroke: (i) the clinical and cost-effectiveness of stroke prevention with left atrial appendage occlusion (LAAO) among persons with atrial ... -
The long-term effects of obstetrical anal sphincter injury on pelvic floor function
Background: As women live longer, the long-term effects of childbirth may negatively affect their quality of life and professional careers. Aim: This thesis investigates the long-term effects of vacuum extraction (VE) ... -
Markers and mechanisms of abnormal neurovascular development in the preterm infant
Background: The extremely preterm infant is at risk of lifelong neurodevelopmental impairments due to brain injuries or abnormal neurovascular development. Mechanisms are largely unknown and biomarkers for adverse outcomes ... -
Outcomes and Experiences of a Fast Track - A direct admission process from ambulance to stroke unit for patients not eligible for acute intervention
Background Stroke is a serious medical condition, and the time before acute intervention and care at stroke units is crucial. People who suffer from a stroke and are not eligible for stroke alert are often transported to ...
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