Sahlgrenska Academy / Sahlgrenska akademin
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Outcomes of invasive treatment in chronic limb-threatening ischaemia
(2023-10-03)Background In chronic limb-threatening ischaemia (CLTI), obstruction of the arterial blood flow causes ischaemic rest pain, ulcers or gangrene in the lower extremities. Patients with CLTI have a substantial risk of ... -
Upper extremity functioning in individuals with cervical or thoracic spinal cord injury - From body functions to participation
(2023-09-28)Background: A spinal cord injury (SCI) can lead to a range of impairments in various body functions, including the function of upper extremity, with severity varying from mild to severe. Long-term consequences for functioning ... -
Infant microbiota and short chain fatty acids - relation to lifestyle and effect on health
(2023-09-21)The commensal microbiota has both beneficial and negative effects on the host. It is a source of infectious and inflammatory microorganisms, but may also provide immune stimulation during a critical period during early ... -
Obesity and IVF outcome. The hope of improvements through weight reduction
(2023-09-20)Background: Female obesity is associated with decreased live birth rate (LBR) after in vitro fertilization (IVF) and adverse maternal and perinatal outcomes are increased in obese women compared to normal weight women after ... -
Short- and long-term outcomes after aneurysmal subarachnoid hemorrhage
(2023-09-15)Aneurysmal subarachnoid hemorrhage (aSAH) is a sudden and devastating event with significant morbidity and mortality. The development of delayed cerebral ischemia (DCI) is a major contributor to the observed high morbidity. ... -
On oral health before and after obesity treatment
(2023-09-12)The overall aim of this thesis was to study the oral health of individuals with obesity and how oral health may be affected by medical and surgical obesity treatment. The thesis comprises three study populations, with ... -
Suicidality and depression in older adults: Prevalence, predictors, and outcomes
(2023-09-08)Older adults have the highest risk of suicide of all age groups. Depression is a major risk factor for suicide in late life, but is also associated with lower quality of life, somatic disorders, and premature death. The ... -
Left ventricular dysfunction in critically ill patients
(2023-09-08)ABSTRACT Background: Cardiac dysfunction is common in Intensive Care Unit (ICU) patients and can contribute to multiorgan failure and death. Despite this, few studies have been performed on pathogenies, prevalence, ... -
Long-term impact of exposure to sulfur mustard on mental health, quality of life, and lung function
(2023-09-04)Sulfur mustard is a highly harmful blistering chemical warfare agent with an alkylation ability that can affect multiple organs (skin, eyes and lungs) in the short and long term. Sulfur mustard’s long-term biopsychosocial ... -
Gambling, alcohol and gender: Subjective effects and clinical characteristics
(2023-09-01)Gambling and alcohol are two recreational activities enjoyed by many people all over the world. Most with the purpose of leisure and social interaction with little or no consequence to impact daily life. For some however ... -
The relationship between cognition and ESSENCE in childhood
(2023-08-29)Aims: To examine the relationship between cognition and ESSENCE (Early Symptomatic Syndromes Eliciting Neurodevelopmental Clinical Examinations) features in children, ages 7-8 years. To investigate the importance of ... -
How does the technical status of medical ultrasound equipment affect image quality? Studies based on human observer experiments and a novel method for automatic detection of defective transducers
(2023-08-25)Ultrasound as an imaging modality has a fundamental role in modern healthcare. The equipment, especially transducers, is fragile and handled daily, and transducers are known to sometimes become defective. The overall ... -
Checkpoint inhibitor-induced adverse events in the CNS - T-cell characteristics and biomarkers
(2023-08-21)Immune checkpoint inhibitors (ICI) activate T cells to kill cancer cells by blocking inhibitory receptors PD-1 (nivolumab; nivo) or CTLA-4 (ipilimumab; ipi). Activated T cells can also attack any healthy organ, causing ... -
Dietary patterns linked to symptoms in patients with a disorder of gut-brain interaction
(2023-08-18)Disorders of gut-brain interaction (DGBI) encompass a range of medical conditions characterized by gastrointestinal (GI) symptoms, in the absence of alarm features or organic diseases that explain the symptoms, after a ... -
Pre/Peri/Earl-Life Exposures and Early Child Neurodevelopment: Results from the Japan Environment and Children's Study (JECS)
(2023-08-18)Background: Combinations of genetic and environmental factors contribute to aetiologies of neuropsychiatric problems and neurodevelopmental disorders (NDDs) in intricate manners. Among the environmental factors, exposures ... -
Bone health and nutrition treatment. Studies on young women with anorexia nervosa and children with epilepsy
(2023-08-17)Background: Adequate nutritional status is crucial for optimal longitudinal growth and accrual of bone mass during childhood and adolescence. Peak bone mass achieved in young adulthood affects bone health throughout life. ... -
Degenerative cervical myelopathy: Surgical treatment, imaging evaluation, and outcome
(2023-08-16)Degenerative cervical myelopathy (DCM) is the most common cause of spinal cord impairment in adults worldwide. The overall aims of this thesis were to compare patient-reported clinical outcomes, adverse events, and ... -
Effects of silicon on bone. Clinical observations and experimental cell studies.
(2023-08-16)Bone health has a major impact on life quality. In Sweden, osteoporosis is a highly prevalent skeletal disease that primarily affects the elderly, causing fragility fractures and pain. Local pathological bone defects due ... -
Early detection of critical congenital heart defects in Sweden - with a focus on coarctation of the aorta
(2023-05-30)Introduction: Despite the implementation of prenatal and neonatal screening, newborn infants with critical congenital heart defects (CCHD) remain at risk of being discharged undiagnosed, particularly newborns with coarcation ... -
Oropharyngeal dysphagia in adults: Prevalence, professional practices, patient perspectives and treatment outcomes
(2023-05-25)Background: Oropharyngeal dysphagia (OD) is defined as any disruption in the transportation of food/liquids safely and efficiently from the mouth, through the pharynx and into the esophagus. The underlying causes of OD ...