Sahlgrenska Academy / Sahlgrenska akademin
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Myringoplasty. Studies on surgical and patient-related outcomes
(2025-03-27)A tympanic membrane (TM) perforation can lead to hearing loss and recurrent ear infections. Myringoplasty, a surgical procedure aiming to heal the perforation, is performed on approximately 800 individuals annually in ... -
Evaluations of Monte Carlo and AI Techniques for SPECT Reconstruction
(2025-03-21)Molecular radiotherapy is an effective treatment that uses radionuclides bound to molecules that selectively target specific tumor types. SPECT imaging in molecular radiotherapy enables dosimetry, allowing for the estimation ... -
Maternal Dietary Intake and Associated Pregnancy Outcomes in the United Arab Emirates - The Dietary Subcohort of the Mutaba’ah Study
(2025-03-21)This thesis aimed to assess dietary intake and its associations with pregnancy outcomes in the United Arab Emirates (UAE). Within the Mutaba’ah Study, 1556 pregnant women were recruited into a dietary subcohort. Data ... -
Effects of contrast media on renaI and thyroid function - and the impact of thyroid nodules
(2025-03-21)The risk of renal damage by iodine contrast media (ICM) has long been discussed but there is still controversy about whether contrast-induced acute kidney injury (CI-AKI) exists. ICM-induced thyroid dysfunction is a less ... -
Patient characteristics and their impact on recovery after acute Achilles tendon rupture
(2025-03-17)The incidence of acute Achilles tendon rupture has increased in the Swedish population. The median age at injury onset is roughly 50 years, with a male-to-female ratio of approximately 4:1. Acute Achilles tendon rupture ... -
Long-term Mental Health and Multimorbidity Outcomes in 22q11.2 deletion syndrome - A Comprehensive Study from Childhood to Adulthood
(2025-03-17)22q11.2 deletion syndrome (22q11.2DS) is a genetic disorder with a markedly diverse phenotype. Aims: Examine mental health and multimorbidity in adults with 22q11.2DS followed prospectively from childhood/young adult age ... -
Artificial intelligence-based organ and tumour segmentation in prostate cancer patients. Studies on PET/CT and pre-treatment CT scans.
(2025-03-11)Aim: This thesis aimed to evaluate the prognostic and clinical significance of artificial intelligence (AI)-based segmentation and quantification of the prostate, the prostate tumour and the surrounding risk organs (OARs), ... -
Genodermatoses: Epidemiology and application of advanced laser microscopy techniques
(2025-03-11)Genodermatoses encompass a wide range of hereditary skin disorders that significantly affect the quality of life of patients and pose substantial challenges for research. Most genodermatoses are rare, and their incidence ... -
Applying Prediction Models and AI to Optimize Growth Hormone Therapy in Children with Short Stature
(2025-03-04)ABSTRACT Background: Growth hormone (GH) therapy has revolutionized the management of short stature in children, offering improved growth outcomes for those with GH deficiency and other related conditions. This thesis ... -
Health improvement in chronic widespread pain. Outcomes and experiences
(2025-03-04)Aim: The purpose of this thesis was to investigate changes in health outcomes and experiences of improvement over time and the effect of person-centred physical activity delivered with digital e-health support on health ... -
On marginal bone resorption around oral implants
(2025-03-04)The etiology of marginal bone loss (MBL) around osseointegrated implants remains controversial. Despite extensive research, the initiating causes of MBL are unclear. Long-term clinical studies challenge the notion that ... -
Patient safety and person-centeredness in healthcare for patients with suicidal behavior
(2025-03-04)Ensuring patient safety is a cornerstone of high-quality care for individuals experiencing suicidal behavior. Traditionally focused on risk reduction, safety efforts may unintentionally erode trust when overly security-driven. ... -
Psychological perspectives on breast reconstruction: patient reported outcomes and effects of complications
(2025-03-04)The overall aim of the thesis was to increase the understanding of women’s experiences of breast reconstruction. Women undergoing mastectomy and breast reconstruction participated in paper I, II and IV. Paper I was a ... -
Memory B cell dynamics after respiratory viral infections
(2025-02-27)Viral respiratory infections continue to be a global health burden with high mor- bidity and mortality. With two viral pandemics with only 10 years apart, by Influenza A virus, 2009, and SARS-CoV2 emerging 2019, and ... -
Gut-brain peptides and drugs of abuse: highlighting the role of GLP-1 and amylin
(2025-02-27)Alcohol use disorder (AUD) and cocaine use disorder (CUD) are complex conditions with diverse neurobiological foundations. Current treatments for AUD and CUD are suboptimal; gaining a deeper understanding of the underlying ... -
Taming the masses: Proteomic profiling across the spectrum and stages of neurodegenerative diseases
(2025-02-25)Neurodegenerative diseases (NDs) are a group of brain-related disorders that mainly affect individuals of older age. They are characterized by a progressive loss of neurons, which ultimately results in a wide array of ... -
Detecting and Localizing Prostate Cancer with MRI
(2025-02-18)The overall objective of this thesis is to evaluate MRI as a diagnostic tool for prostate cancer, with a particular focus on quantitative parametric analysis and segmentation of prostate magnetic resonance (MR) images, and ... -
Urinary tract infection in infants - Studies on management and genetic susceptibility
(2025-02-18)Urinary tract infection (UTI) in infants is associated with kidney damage. Recommendations on investigations to identify patients at risk of recurrent UTIs and kidney related morbidity vary considerably. The objectives of ... -
Neutrophil free fatty acid receptors
(2025-02-18)The human immune system protects against threats that range from microorganisms to damaged cells. Neutrophils, which are the most numerous cells of the innate immune system, circulate in the bloodstream in abundance. In ... -
On the classification, epidemiology, and outcome of acetabular fractures
(2025-02-13)Acetabular fractures were traditionally managed non-surgically, largely due to the absence of effective surgical methods. Since the 1960’s, the field of acetabular fracture surgery has undergone rapid advancements. The ...
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