• ldentification of viruses, their viability and purification in drinking water 

  Saguti, Fredy (2024-10-14)

  This thesis aimed to identify viruses commonly found in water sources and assess the efficiency of water barriers in viral reduction at drinking water treatment plants (DWTPs) over time. Cell culture assays and molecular ...

• Artificial intelligence in assessment of skin tumours in digital pathology 

  Siarov, Jan (2024-10-14)

  The rising incidence of skin cancers has led to an increased burden on dermatopathology laboratories. The advent of digitalization offers the opportunity to integrate artificial intelligence (AI) into digital pathology ...

• Targeting Glutathione metabolism in cancer - a new therapeutic approach 

  Garellick, Viktor (2024-10-14)

  Antioxidants have long been considered as potential cancer-preventive agents, though most clinical trials have failed to demonstrate significant benefits from antioxidant supplements. Recent scientific findings, however, ...

• Laparoscopic lavage in Swedish routine care 2016-2018. The LapLav study 

  Samuelsson, Andreas (2024-10-02)

  Aim: The aim of the thesis was to compare laparoscopic lavage with resection surgery for perforated diverticulitis. Method: All patients operated for perforated diverticulitis in Sweden between 2016-2018 were identified ...

• The alpha 7 nicotinic acetylcholine receptor in cardiovascular disease 

  Mjörnstedt Lyster, Filip (2024-09-26)

  The alpha 7 acetylcholine nicotinic receptors (α7nAChRs) are expressed on human leukocytes and regulate inflammation. Consequently, the α7nAChRs are potential pharmacological targets for several inflammatory diseases. ...

• Frailty in Older Adults in China -Trajectories, Determinants, and Impacts on Healthcare Utilization and Mortality 

  Guo, Yanfei (2024-09-26)

  Frailty, though not a disease in itself, often precedes the onset of illness and is frequently overlooked. Research has paid insufficient attention to frailty as a dynamic phenomenon, particularly its longitudinal changes. ...

• Determinants and risk factors for early risk stratification and optimal secondary pevention in ischemic heart disease 

  Sakalaki, Maria (2024-09-26)

  Background: Ischemic heart disease is the leading cause of death globally. To combat ischemic heart disease and its challenges we must improve secondary prevention for those already affected and prevent its onset in a ...

• Outcomes of chronic and vertically acquired occult hepatitis B 

  Eilard, Anders (2024-09-26)

  Background: Chronic hepatitis B virus (HBV) infection is one of the major chronic infections and still in 2017 the most common cause for liver cirrhosis and hepatocellular carcinoma (HCC, liver cancer) in the world. Occult ...

• Flap-based breast reconstruction: clinical studies on donor sites, patient satisfaction, and health economics 

  Löfstrand, Jonas (2024-09-24)

  Background: Breast cancer is the most common cancer in women. Surgical treatment involves resection of a portion or the whole breast. There are multiple ways to reconstruct a breast, most commonly with implants or transfer ...

• Social and motor coordination: methods development and applications in ESSENCE 

  Thorsson, Max (2024-09-24)

  This thesis aimed to develop and apply methods for evaluating social and motor coordination, domains that often are challenged in individuals with neurodevelopmental/neuropsychiatric disorders (NDDs), also referred within ...

• Survival of patients with glioblastoma - advancements in the past two decades 

  Fekete, Boglarka (2024-09-24)

  Background: Glioblastoma is the most common and most aggressive form of primary malignant brain tumors in adults. The prognosis is generally poor, with a median survival of around 15-16 months, even with aggressive multimodal ...

• Bacterial and Host Factors in Staphylococcus aureus Septic Arthritis 

  Hu, Zhicheng (2024-09-23)

  The intense battle against Staphylococcus aureus (S. aureus) infections, along with the ongoing struggle to develop new effective treatments, presents a major challenge for the healthcare system. This highly pathogenic ...

• Role of Gremlin1 and Bone Morphogenic Protein 4 (BMP4) in metabolic diseases 

  Khatib Shahidi, Roxana

  Gremlin1, a protein highly expressed in human adipocytes, plays a key role in the differentiation of precursor cells into white adipose tissue and is linked to insulin resistance in hypertrophic obesity. This study ...

• Respirable crystalline silica 

  Boers, Daisy (GÖTEBORGS UNIVERSITET, 2024-09-10)

  Crystalline silica is abundant in nature and used in a variety of industries, e.g., mining, farming, construction, foundry processes and production of glass, artificial stone, ceramics and cement. When cut or crushed, dust ...

• Profiling Circulating T cells and Tumor Landscape for Predicting Responses to PD-1 blockade in Patients with Non-Small Cell Lung Cancer 

  Dutta, Nikita (2024-09-05)

  Immune checkpoint blockade (ICB) has significantly improved outcomes in non-small cell lung cancer (NSCLC), yet only a subset of patients achieves durable responses. This underscores the need for effective methods to assess ...

• Food-related symptoms, dietary interventions, and importance of the gut microenvironment in IBS 

  Algera, Joost P. (2024-08-29)

  Irritable bowel syndrome (IBS) is characterized by chronic gastrointestinal (GI) symptoms, including abdominal pain and altered bowel habits i.e., constipation and diarrhea. The pathophysiology is complex and multifactorial ...

• Prostate Biopsy - Cancer detection and risk of complications 

  Örtegren, Joakim (2024-08-29)

  The overall aim of this thesis was to investigate if a sampling protocol with anterior biopsies of prostate increase cancer detection at first repeat biopsy, to evaluate if a clinical routine with urine culture prior to ...

• Biomaterial-induced inhibition of Staphylococcus aureus biofilm formation 

  Turner, Adam Benedict (2024-08-23)

  Biomaterial-associated infection (BAI) is a severe complication linked to medical device implantation, causing significant patient suffering and high healthcare costs. The pathogenesis of BAI is complex and not fully ...

• lnvestigating the functions of Anaplastic Lymphoma Kinase in neuronal tissues 

  Sukumar, Sanjay Kumar (2024-08-23)

  Receptors play an important role in cell-to-cell communication and are critical to the development and homeostasis of multicellular organisms. Anaplastic Lymphoma Kinase (ALK) is an evolutionary conserved receptor tyrosine ...

• Thoracic Mobility in Cystic Fibrosis Care 

  Sinderholm Sposato, Niklas (2024-08-19)

  Introduction: Cystic fibrosis (CF) is an incurable and highly life-limiting hereditary disease. However, due to significant medical advancements over recent decades, life expectancy has risen to close to 50 years. As such, ...

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