• Biomarker profiling in sepsis diagnostics 

  Irani Shemirani, Mahnaz (2024-11-28)

  Effective and timely antibiotic therapy for sepsis requires a thorough understanding of the types and molecular characteristics of bacterial strains. Therefore, we investigated diagnostic strategies to facilitate faster ...

• The roles of RNA m6A modification in disease mechanisms of high-risk neuroblastoma 

  Thombare, Ketan (2024-11-21)

  Epitranscriptomics involves covalent modifications of RNA bases, with N6-methyladenosine (m6A) being one of the most abundant and functionally characterized. This modification plays a key role in RNA metabolism, cellular ...

• Human B-cell development at the single-cell level 

  Sundell, Timothy (2024-11-21)

  B cells play an integral part of our immune system. In adults they develop in the bone marrow in a regulated process in which the specificity of their B-cell antigen receptor (BCR), a membrane bound antibody, is established. ...

• Team-based rehabilitation in primary care for patients with musculoskeletal disorders Experiences, effect- and process evaluation 

  Ekhammar, Annika (2024-11-20)

  Most people will experience musculoskeletal disorders at some point in their lives, ranging from a manageable problem to significant difficulties with mobility, sleeping, performing daily activities, and working. There is ...

• Prerequisites and effects of an opioid-free anaesthesia pathway in patients undergoing bariatric surgery 

  Olausson, Alexander (2024-11-20)

  Obesity is an escalating public health concern and bariatric surgery remains the only effective long-term treatment for substantial weight reduction. However, bariatric surgery typically involves opioid use during and ...

• Exploring pain, fatigue and physical activity in adolescents with Hypermobility Spectrum Disorder or hypermobile Ehlers-Danlos Syndrome 

  Schubert Hjalmarsson, Elke (2024-11-19)

  Adolescents with Hypermobility Spectrum Disorder (HSD) and hypermobile Ehlers–Danlos Syndrome (hEDS) — two overlapping hereditary connective-tissue disorders characterized by joint hypermobility, chronic pain, impaired ...

• Characterization and impact of disorders of gut-brain interaction: a national and international epidemiological project 

  Thind Tornkvist, Navkiran (2024-11-19)

  Disorders of gut-brain interaction (DGBI) are highly prevalent conditions, characterized by chronic or recurrent gastrointestinal (GI) symptoms. DGBI significantly impacts quality of life (QoL) and healthcare utilization, ...

• Kariesriskfaktorer och riskindikatorer hos förskolebarn 

  Ingemansson Hultquist, Ann (2024-11-19)

  Background and aim: Caries is one of the most common diseases in preschool children. Pain, infections and sleep disturbances in childhood caries can adversely affect body weight and nutritional ability and may raise the ...

• DNA damage in autoimmunity 

  Chandrasekaran, Venkataragavan (2024-11-18)

  Rheumatoid arthritis (RA) is the canonical autoimmune disease whose pathogenesis is tightly linked to risk factors which cause damage of DNA and affect immune cell function. DNA damage abnormally reorganizes the genome and ...

• Tobacco control policies in Vietnam: Smoking behaviors and stakeholders' perceptions 

  Nguyen, Thi Ngoc Phuong (2024-11-18)

  Tobacco remains a significant public health concern in Vietnam, particularly among men, with over 15 million users. It has been 12 years since the tobacco control law was enacted; however, the smoking prevalence has decreased ...

• Clinical outcome and ethical perspectives of internationally adopted children with cleft lip and palate 

  Sahlsten Schölin, Johnna (2024-11-18)

  ABSTRACT This thesis aimed to evaluate clinical outcomes regarding surgery, craniofacial growth, speech and hearing, in internationally adopted children (IAC) with cleft lip and/or palate. An ethical analysis of the ...

• Surveilling Hearts - A New Biomarker for the Non-Invasive Diagnosis of Rejection after Heart Transplantation 

  Böhmer, Jens (2024-11-18)

  Introduction: Heart transplantation (HTx) is the ultimate treatment for advanced heart failure. Survival after HTx is hampered by rejection. Endomyocardial biopsies (EMB) are the cornerstone of surveillance after HTx to ...

• The social determinants of self-reported mental health among adolescents in Sweden and the Nordic countries - focusing on socioeconomic inequalities 

  Corell, Maria (2024-11-14)

  Mental health problems have increased among children and adolescents in the Nordic countries during the last decades. Such problems may have both short- and long-term negative consequences for both the individual and society ...

• Local Recurrence of Rectal Cancer: Risk factors, diagnosis and Quality of Life 

  Waldenstedt, Sophia (2024-11-13)

  Aim To explore different aspects of local recurrence of rectal cancer, including intraoperative adverse events as a risk factor, symptoms and diagnosis, survivorship issues and Quality of Life, and to validate data on local ...

• Osteocalcin and Parental Perceptions. Childhood osteocalcin and its association to early growth, body composition and neurodevelopment along with parental perceptions on childhood overweight and obesity 

  Berggren, Sara (2024-11-12)

  Background and aims: Early programming mean that environmental factors, hormonal levels and early life experiences, like feeding practices, during the first years of life, may have long-lasting effects on later health. One ...

• Improving the hand hygiene of healthcare workers: Exploring the feasibility of an electronic monitoring system 

  Granqvist, Karin (2024-11-12)

  Technical innovations, such as electronic monitoring systems (EMSs), have been developed to promote increased hand hygiene (HH) adherence among healthcare workers (HCWs). The overall aim of this thesis was to explore the ...

• Novel biomarkers for parkinsonian disorders 

  Fernandes Gomes, Bárbara (2024-11-12)

  Parkinsonian disorders (PS) are a heterogeneous group of neurodegenerative diseases characterised by the presence of parkinsonism. Parkinson’s disease (PD) is the most common PS, characterised by the accumulation of ...

• Endocrine and neural mechanisms in metabolic control 

  Asker, Mohammed (2024-11-11)

  The regulation of eating behavior and metabolism is governed by complex inter-actions between central and peripheral signals, with hormones such as oxytocin (OT) and glucagon-like peptide-1 (GLP-1) playing pivotal roles. ...

• Tumor metastasis: mechanisms and prevention 

  Paul, Sanchari (2024-11-07)

  Metastatic spread of tumor cells accounts for the majority of cancer-related deaths. We have developed cancer vaccines based on the immunostimulatory adjuvant cholera toxin A1 (CTA1), including vaccines that deliver tumor ...

• Translational aspects of Gastrointestinal stromal tumors 

  Berndsen, Marta (2024-11-07)

  Gastrointestinal stromal tumor (GIST) is the most common mesenchymal tumor of the gastrointestinal tract, driven by mutations in KIT and PDGFRA in the majority of cases. This thesis explores several translational ...

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