• Mechanisms of mucosal injury and repair in intestinal transplantation 

  Bagge, Jasmine (2025-12-04)

  Intestinal transplantation faces challenges due to high risk of life-threatening complications following transplantation. Ischemia-reperfusion injury is a major cause of early morbidity and complications. By introducing a ...

• Oral care in older adults with care needs: Assessing interventions and exploring experiences and perceptions in municipal old age care 

  Johansson, Isabelle (2025-12-01)

  Oral health is significant for overall health and quality of life. Older adults live longer and keep their natural teeth to a greater extent. Oral health and oral hygiene among older adults residing in nursing homes is ...

• Goblet cell-intrinsic colonic defense 

  Venkita Subramani, Mahadevan (2025-11-28)

  The intestine is constantly exposed to billions of commensal microbes as well as pathogens and opportunistic organisms. Protection of the epithelium depends on the mucus barrier, produced by goblet cells (GCs), which ...

• Exploration of biomarker candidates in epithelial ovarian cancer with special reference to the prognostic role of LMTK3 

  Ittner, Ella (2025-11-28)

  The growing integration of molecular profiling and data-driven analysis has opened new opportunities for precision oncology. In epithelial ovarian cancer (EOC), however, translating these molecular insights into clinically ...

• Exploring the role of co-driver mutations in cancer: Implications for precision medicine 

  Dzanan, Jozefina (2025-11-25)

  Cancer develops through driver mutations, genetic alterations that promote tumor initiation and growth. However, additional co-driver mutations can profoundly modify tumor behavior, metabolism, and therapy response. This ...

• Applied mass spectrometry-based proteomics in infectious diseases 

  Acha Alarcon, Leonarda (2025-11-25)

  Infectious diseases caused by bacterial pathogens are common, and their impact can be measured in economic losses, but more importantly, in the loss of lives and the deterioration of quality of life, as they remain among ...

• Advanced phenotyoing of cardiovascular risk in children with chronic disease- Children with type 1 diabetes and kidney transplant recipients 

  Bergdahl, Ebba (2025-11-20)

  Abstract This thesis aim to determine the presence of early vascular changes in two paediatric cohorts with chronic disease and highly elevated cardiovascular risk, children with kidney transplants (Paper I) and ...

• Structural studies of mitochondrial DNA polymerase γ 

  Valenzuela, Sebastian (2025-11-20)

  Mitochondria are essential eukaryotic organelles that generate most of the cell’s adenosine triphosphate (ATP), the energy currency used to power cellular activities. Because mitochondria are descendants of once free-living ...

• Digital cardiovascular health education among school-going adolescents in Nepal: the HRIDAYA project 

  Shakya, Dayana (2025-11-19)

  Background The burden of cardiovascular diseases (CVD) and its risk factors are increasing among adolescents. The life course approach to CVD prevention necessitates targeted intervention among adolescents. Aims This ...

• Metaorganismal perspective on cardiometabolic diseases 

  Pradhan, Meenakshi (2025-11-19)

  The gut microbiota is increasingly recognized as an important factor affecting host health, with alterations linked to the development of cardiometabolic diseases. This thesis investigates how gut microbial composition and ...

• Inflammation and immunomodulation related to materials and extracellular vesicles 

  Philip, Jincy (2025-11-19)

  Cell-to-cell communication is a fundamental process at the implant–tissue interface. This communication is shaped by implant properties or by extracellular vesicles (EVs) that transfer regulatory cargo between cells. ...

• Workplace support and the return-to-work process for patients with stress-related mental disorder 

  Beno, Anja (2025-11-18)

  Background: Sick leave with psychiatric diagnoses has increased markedly in Sweden over the past two decades, with stress-related mental disorders now accounting for around 20% of all ongoing cases. A similar trend is ...

• Dynamic cerebral autoregulation and endothelial dysfunction in preeclampsia 

  Carlberg, Niclas (2025-11-18)

  Background: Preeclampsia affects approximately 1 in 20 pregnant women and may cause severe morbidity and mortality in both mother and fetus. The pathophysiology remains partly unclear, and the clinical course is highly ...

• Application of hydrogen peroxide photolysis for reduction of cariogenic biofilm activity 

  Shirato, Midori (2025-11-18)

  Dental caries is a multifactorial disease, and cariogenic biofilms play a crucial role in lesion development. Therefore, managing cariogenic biofilms is essential, and the development of novel and effective antimicrobial ...

• Molecular aspects of asthma in adults: allergen components and eosinophil-derived neurotoxin 

  Ozuygur Ermis, Saliha Selin (2025-11-18)

  Identification of asthma phenotypes has become pivotal to providing better disease management, as it enables the implementation of precision medicine-based approaches. Biomarkers are essential in connecting asthma ...

• High-frequency, high intensity transcutaneous electrical nerve stimulation for postoperative pain - evaluating a new treatment regime and a clinical bedside prediction test in outpatient surgery. 

  Ögren, Cecilia (2025-11-17)

  Abstract The incidence of postoperative pain is high, even after minor surgery, despite multimodal analgesic treatment plans. The aim of this thesis is to explore ways to improve postoperative pain in outpatient surgery. Study ...

• Prostate Cancer Screening – Attendance and Psychological Consequences 

  Svensson, Linda (2025-11-14)

  Participation in prostate cancer screening may confer both benefits and harms, which can be perceived and weighed differently by individual men. The blood test PSA (prostate-specific antigen) may provide reassurance when ...

• Improved fracture prediction by identifying and integrating novel risk factors in fracture risk assessment. 

  Zoulakis, Michail (2025-11-12)

  Abstract Osteoporosis causes significant morbidity and healthcare costs through fragility fractures, with substantial gaps remaining in fracture risk assessment, particularly in older women. This thesis presents four ...

• Molecular Insights in Oral Leukoplakia: Epigenetic, Immunological and Proteomic Perspectives. 

  Ganesh, Divya (2025-11-12)

  Oral leukoplakia, a potentially malignant oral disorder, with a risk of transformation into oral squamous cell carcinoma (OSCC). This thesis investigates the molecular, immunological, and proteomic alterations in ...

• Pelvic floor trauma after childbirth - Risk factors, surgical treatment and prevention 

  Larsudd-Kåverud, Jennie (2025-11-11)

  Background: As women live longer, the long-term effects of childbirth may negatively affect their quality of life and professional careers. Aim: The overall objective of this thesis was to examine how childbirth-related ...

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