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Unravelling the complexity of cold acclimation in plants
(2011-05-19)
Many plants respond to low non-freezing temperatures by increasing their freezing tolerance in a process known as cold acclimation. Microarray studies have shown that hundreds of genes are differentially expressed during ...
Protein Damage Control during Embryonic Stem Cell Differentiation: Role of the Proteasome
(2011-05-11)
During the lifespan of organisms ranging from yeast to humans, there is an accumulation of macromolecular damage. However, these organisms produce youthful progeny with low damage levels. This thesis focuses on how this ...
The Importance of a Fifth Element in Transcription: Transcriptional Discrimination in Escherichia coli
(2011-04-08)
Upon growth arrest of the bacterium Escherichia coli, RNA polymerase (Es70) is redirected from transcribing genes encoding the protein synthesizing system (PSS) to those involved in maintenance and stress resistance. The ...
Post-transcriptional regulation after stress in Schizosaccharomyces pombe
(2011-03-18)
Post transcriptional regulation is part of the gene expression control and is important for many cellular processes. It influences how mRNAs are selected for translation, degradation or storage. In this thesis, I describe ...